Sclerosing cholangitis and systemic lymphadenopathy

A 48-year-old man was admitted to our hospital with jaundice and systemic lymphadenopathy. Cholangiographic findings and liver histology disclosed the presence of sclerosing cholangitis. The patient also had a marked polyclonal increase in IgG levels. The cholangiographic findings, the systemic lymp...

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Bibliographic Details
Published in:Journal of gastroenterology 2001-06, Vol.36 (6), p.429-432
Main Authors: Kazumori, H, Hashimoto, T, Akagi, S, Adachi, K, Watanabe, M, Kinoshita, Y
Format: Article
Language:English
Subjects:
Cholangitis, Sclerosing - complications
Humans
Lymphatic Diseases - complications
Lymphatic Diseases - immunology
Male
Middle Aged
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Summary:A 48-year-old man was admitted to our hospital with jaundice and systemic lymphadenopathy. Cholangiographic findings and liver histology disclosed the presence of sclerosing cholangitis. The patient also had a marked polyclonal increase in IgG levels. The cholangiographic findings, the systemic lymphadenopathy, and the increase in IgG levels resolved completely after treatment with prednisolone. This case suggests that there is an association between sclerosing cholangitis and immunologic abnormalities, and that corticosteroid treatment is useful for this disorder.
ISSN:0944-1174
1435-5922
DOI:10.1007/s005350170089