Radiotherapy for Genital Extramammary Paget's Disease in Situ

Background. Radiotherapy as a first‐choice treatment for extramammary Paget's (EMP) disease in situ has been seldom used. Objective. To review the most relevant aspects of radiotherapy as first‐choice treatment in selected cases of anogenital EMP disease in situ. Methods. Two men with an age ra...

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Bibliographic Details
Published in:Dermatologic surgery 2001-06, Vol.27 (6), p.587-590
Main Authors: Moreno‐Arias, G. A., Conill, C., Castells‐Mas, A., Arenas, M., Grimalt, R.
Format: Article
Language:English
Subjects:
Aged
Biological and medical sciences
Diseases of the skin. Cosmetics
Genitalia, Male
Humans
Male
Medical sciences
Paget Disease, Extramammary - pathology
Paget Disease, Extramammary - radiotherapy
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Skin Neoplasms - pathology
Skin Neoplasms - radiotherapy
Treatment Outcome
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Summary:Background. Radiotherapy as a first‐choice treatment for extramammary Paget's (EMP) disease in situ has been seldom used. Objective. To review the most relevant aspects of radiotherapy as first‐choice treatment in selected cases of anogenital EMP disease in situ. Methods. Two men with an age range of 71–79 years (mean age 75 ± 5.6 years) with EMP disease in situ localized in the genital region were treated by means of X‐rays of 100 kV, 440 cGy/day, 3 days a week over 3 weeks until a total dose of 3960 cGy was completed. Results. Complete regression of EMP disease in situ was observed in both patients after radical radiation therapy and neither local recurrences nor internal malignancies have been documented. Conclusion. Radiotherapy is a curative treatment in selected cases of EMP disease in situ affecting large areas of the anogenital region.
ISSN:1076-0512
1524-4725
DOI:10.1046/j.1524-4725.2001.00304.x