Color Doppler imaging of untreated and irradiated choroidal melanomas

We examined untreated and irradiated choroidal melanomas with color Doppler imaging (CDI), a noninvasive method providing quantitative measures of blood flow, to determine if the tumor vessel damage associated with irradiation can be detected using this technology. CDI was performed on 122 untreated...

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Bibliographic Details
Published in:European journal of ophthalmology 2001-04, Vol.11 (2), p.150-155
Main Authors: REGAN, S, EGAN, K. M, HART, L, GRAGOUDAS, E. S
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
Biological and medical sciences
Blood Flow Velocity
Choroid Neoplasms - blood supply
Choroid Neoplasms - diagnostic imaging
Choroid Neoplasms - radiotherapy
Female
Humans
Laser-Doppler Flowmetry
Male
Medical sciences
Melanoma - blood supply
Melanoma - diagnostic imaging
Melanoma - radiotherapy
Middle Aged
Neovascularization, Pathologic - diagnostic imaging
Neovascularization, Pathologic - pathology
Ophthalmology
Protons
Radiotherapy, High-Energy
Tumors and pseudotumors of the eye, orbit, eyelid, lacrimal apparatus
Ultrasonography, Doppler, Color
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Summary:We examined untreated and irradiated choroidal melanomas with color Doppler imaging (CDI), a noninvasive method providing quantitative measures of blood flow, to determine if the tumor vessel damage associated with irradiation can be detected using this technology. CDI was performed on 122 untreated and 76 previously irradiated tumors using a Q2000 color Doppler ultrasound unit. Spectral analysis was performed on all detectable vascular regions within the tumor to obtain estimates of the peak systolic and end diastolic flow velocities and resistive index ((syst-diast)/syst). Vessels were detected in 93% of the untreated tumors and in 63% of the treated tumors (p
ISSN:1120-6721
1724-6016
DOI:10.1177/112067210101100208