The importance of grade 2 ischemic mitral regurgitation in coronary artery bypass grafting

• Published in: European journal of cardio-thoracic surgery 2001-08, Vol.20 (2), p.276-281
• Main Authors: Rydén, Tina, Bech-Hanssen, Odd, Brandrup-Wognsen, Gunnar, Nilsson, Folke, Svensson, Sveneric, Jeppsson, Anders
• Format: Article
• Language: English
• Subjects: Aged; Cardiac surgery; Coronary Artery Bypass; Coronary artery disease; Coronary Disease - complications; Coronary Disease - surgery; Echocardiography; Echocardiography, Doppler; Female; Humans; Male; Middle Aged; Mitral regurgitation; Mitral Valve Insufficiency - diagnostic imaging; Mitral Valve Insufficiency - etiology; Mitral Valve Insufficiency - surgery; Postoperative Period
• ISSN: 1010-7940; 1873-734X
• DOI: 10.1016/S1010-7940(01)00770-9

Objective: To study if grade 2 ischemic mitral regurgitation (MR) influences outcome after coronary artery bypass grafting (CABG). Methods: Results of all CABG patients with grade 2/4 ischemic MR operated during 1995–1998 (n = 89) were compared with all CABG patients without MR (n = 4709) during the same period. To further evaluate patients with grade 2 ischemic MR, a case-control study focusing on functional status was performed. Control patients without MR (n = 89) were matched for age, gender and left ventricular ejection fraction. All patients were interviewed regarding angina symptoms and functional status. Results: Survival according to Kaplan–Meier at 1 and 3 years were inferior in the MR group compared to all CABG patients (91 vs 96% and 84 vs 92%, respectively (P = 0.0017). However, MR patients were older (68±9 vs 65±9 years (mean±SD), P = 0.008) and had an inferior preoperative left ventricular ejection fraction (42±14 vs 58±14%, P