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Hippocampus formation: an intriguing collaboration
Recent genetic studies have shown that the signalling factor Wnt3a is required for formation of the hippocampus; the developmental consequences of Wnt signalling in the hippocampus are mediated by multiple HMG-box transcription factors, with LEF-1 being required just for formation of the dentate gyr...
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Published in: | Current biology 2000-04, Vol.10 (7), p.R279-R281 |
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container_end_page | R281 |
container_issue | 7 |
container_start_page | R279 |
container_title | Current biology |
container_volume | 10 |
creator | Roelink, H |
description | Recent genetic studies have shown that the signalling factor Wnt3a is required for formation of the hippocampus; the developmental consequences of Wnt signalling in the hippocampus are mediated by multiple HMG-box transcription factors, with LEF-1 being required just for formation of the dentate gyrus. |
doi_str_mv | 10.1016/s0960-9822(00)00407-3 |
format | article |
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ispartof | Current biology, 2000-04, Vol.10 (7), p.R279-R281 |
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language | eng |
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source | BACON - Elsevier - GLOBAL_SCIENCEDIRECT-OPENACCESS |
subjects | Animals DNA-Binding Proteins - genetics Embryonic Induction High Mobility Group Proteins - genetics Hippocampus - embryology LEF-1 protein Lymphoid Enhancer-Binding Factor 1 Mice Mice, Mutant Strains Proteins - genetics Transcription Factors - genetics Wnt Proteins Wnt-3a protein Wnt3 Protein Wnt3A Protein |
title | Hippocampus formation: an intriguing collaboration |
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