PCR fingerprinting analysis for differentiation of Streptococcus pneumoniae reinfection versus relapse

Polymerase chain reaction fingerprint profiles of isolates obtained during an episode of pneumococcal pneumonia with bacteremia differed significantly from profiles of isolates obtained from the same patient during a subsequent episode of pneumococcal meningitis with bacteremia. Polymerase chain rea...

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Bibliographic Details
Published in:Diagnostic microbiology and infectious disease 2000-04, Vol.36 (4), p.275-278
Main Authors: Gerardoa, S.Hunt, Citron, D.M., Goldstein, E.J.C.
Format: Article
Language:English
Subjects:
Bacteremia - diagnosis
Bacterial Capsules - analysis
Bacterial diseases
Biological and medical sciences
Bronchoalveolar Lavage Fluid - microbiology
DNA Fingerprinting
DNA, Bacterial - analysis
Female
Human bacterial diseases
Humans
Infectious diseases
Medical sciences
Meningitis, Pneumococcal - blood
Meningitis, Pneumococcal - cerebrospinal fluid
Meningitis, Pneumococcal - diagnosis
Microbial Sensitivity Tests
Pneumonia, Pneumococcal - blood
Pneumonia, Pneumococcal - cerebrospinal fluid
Pneumonia, Pneumococcal - diagnosis
Polymerase Chain Reaction
Recurrence
Serotyping
Sputum - microbiology
Staphylococcal infections, streptococcal infections, pneumococcal infections
Streptococcus pneumoniae - classification
Streptococcus pneumoniae - growth & development
Streptococcus pneumoniae - isolation & purification
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Summary:Polymerase chain reaction fingerprint profiles of isolates obtained during an episode of pneumococcal pneumonia with bacteremia differed significantly from profiles of isolates obtained from the same patient during a subsequent episode of pneumococcal meningitis with bacteremia. Polymerase chain reaction fingerprinting provides a means of differentiating new infection from relapse, and may be a simple molecular tool for comparison of Streptococcus pneumoniae isolates.
ISSN:0732-8893
1879-0070
DOI:10.1016/S0732-8893(00)00114-0