Early pregnancy nausea and vomiting in a high-altitude Andean population

Objectives: We examined the prevalence, risk factors, and maternal-neonatal consequences of early pregnancy nausea and vomiting (NVP) in a high altitude Ecuadorian Andean population. Methods: Subjects were 1000 low-income urban primigravidas who delivered full-term pregnancies. Results: NVP prevalen...

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Bibliographic Details
Published in:International journal of gynecology and obstetrics 2000-04, Vol.69 (1), p.9-21
Main Authors: Weigel, M.M., Caiza, M.E., Lascano, Y., Barreno, G., Mosquera, L.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Altitude
Biological and medical sciences
Confidence Intervals
Diseases of mother, fetus and pregnancy
Ecuador
Ecuador - epidemiology
Female
Gynecology. Andrology. Obstetrics
High altitude
Humans
Intrauterine growth
Medical sciences
Morning sickness
Multivariate Analysis
Nausea - epidemiology
Nutritional status
Odds Ratio
Poverty
Pregnancy
Pregnancy Complications - epidemiology
Pregnancy Outcome
Pregnancy Trimester, First
Pregnancy. Fetus. Placenta
Prevalence
Retrospective Studies
Risk Factors
Tropical medicine
Urban Population
Vomiting - epidemiology
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Summary:Objectives: We examined the prevalence, risk factors, and maternal-neonatal consequences of early pregnancy nausea and vomiting (NVP) in a high altitude Ecuadorian Andean population. Methods: Subjects were 1000 low-income urban primigravidas who delivered full-term pregnancies. Results: NVP prevalence was 67%. Decreased NVP risk was associated with higher altitude and increased risk with less education, common law marriage, and white collar/professional occupation. Lifestyle changes associated with NVP included decreased likelihood of drinking and outside employment but increased probability of prenatal care, supportive living arrangements, and dietary disturbances. NVP had no apparent long-term effect on maternal nutritional status but was associated with increased fetal subcutaneous fat reserves. Conclusions: NVP prevalence and timing was similar to developed populations although some of the identified risk factors were unique to the group. NVP did not appear to have a significant impact on prenatal nutrition at term but was linked with increased fetal fat accumulation.
ISSN:0020-7292
1879-3479
DOI:10.1016/S0020-7292(99)00208-8