Analytical and Clinical Performance of a Detergent-based Homogeneous LDL-Cholesterol Assay: A Multicenter Evaluation

LDL-cholesterol (LDL-C) concentrations currently are determined in most clinical laboratories using the Friedewald calculation. This approach has several limitations and may not always meet the current total error recommendation in LDL-C measurement of

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Bibliographic Details
Published in:Clinical chemistry (Baltimore, Md.) Md.), 2000-04, Vol.46 (4), p.506-514
Main Authors: Nauck, Matthias, Graziani, Maria Stella, Bruton, Deborah, Cobbaert, Christa, Cole, Thomas G, Lefevre, Fabrice, Riesen, Walter, Bachorik, Paul S, Rifai, Nader
Format: Article
Language:English
Subjects:
Analytical, structural and metabolic biochemistry
Bilirubin - analysis
Biological and medical sciences
Cholesterol, LDL - blood
Detergents
Fundamental and applied biological sciences. Psychology
Hemoglobins - analysis
Humans
Lipoproteins, myelin
Postprandial Period
Proteins
Reagent Kits, Diagnostic
Regression Analysis
Triglycerides - blood
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Description
Summary:LDL-cholesterol (LDL-C) concentrations currently are determined in most clinical laboratories using the Friedewald calculation. This approach has several limitations and may not always meet the current total error recommendation in LDL-C measurement of
ISSN:0009-9147
1530-8561
DOI:10.1093/clinchem/46.4.506