Cowpox virus infection in an 11-year-old girl

We describe an 11-year-old girl with a cowpox virus infection, who presented with a 14-day-old crusted, ulcerated nodule on the chin/neck and a 6-day-old eroded blister on the left leg. The girl lived in a rural environment, had close contact to several cats from the neighborhood, and had an atopic...

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Bibliographic Details
Published in:Journal of the American Academy of Dermatology 2000-05, Vol.42 (5), p.892-894
Main Authors: Wienecke, Ralf, Wolff, Hans, Schaller, Martin, Meyer, Hermann, Plewig, Gerd
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
Cats
Child
Cowpox - pathology
Cowpox virus - pathogenicity
Diagnosis, Differential
DNA, Viral - analysis
Female
Human viral diseases
Humans
Infectious diseases
Leg - pathology
Medical sciences
Microscopy, Electron
Neck - pathology
Polymerase Chain Reaction
Skin Diseases - pathology
Skin Diseases - virology
Viral diseases
Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye
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Summary:We describe an 11-year-old girl with a cowpox virus infection, who presented with a 14-day-old crusted, ulcerated nodule on the chin/neck and a 6-day-old eroded blister on the left leg. The girl lived in a rural environment, had close contact to several cats from the neighborhood, and had an atopic predisposition. The presence of orthopox virus in the lesion on the left leg was demonstrated by electron microscopy (negative staining, transmission electron microscopy) and virus isolation. Classification as a cowpox virus was determined by polymerase chain reaction (PCR), followed by restriction enzyme digestion of the PCR product. (J Am Acad Dermatol 2000;42:892-4.)
ISSN:0190-9622
1097-6787
DOI:10.1016/S0190-9622(00)90265-2