Complex vertebral malformation in a holstein calf: report of a case in the USA

Department of Biomedical Sciences, Virginia Polytechnic Institute and State University, Blacksburg 24061, USA. Complex vertebral malformation (CVM), a familial syndrome of Holstein calves, has been reported in aborted fetuses and in prematurely born, stillborn, and neonatal calves. Affected calves h...

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Bibliographic Details
Published in:Journal of veterinary diagnostic investigation 2001-07, Vol.13 (4), p.333-336
Main Authors: Duncan, RB, Jr, Carrig, CB, Agerholm, JS, Bendixen, C
Format: Article
Language:English
Subjects:
Abnormalities, Multiple - pathology
Animals
Animals, Newborn
Arthrogryposis - pathology
Biological and medical sciences
Birth Weight
Cattle - abnormalities
Cattle Diseases - pathology
Cervical Vertebrae - abnormalities
Female
Fundamental and applied biological sciences. Psychology
Heart Defects, Congenital - pathology
Metacarpophalangeal Joint - abnormalities
Microbiology
Syndrome
United States
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Summary:Department of Biomedical Sciences, Virginia Polytechnic Institute and State University, Blacksburg 24061, USA. Complex vertebral malformation (CVM), a familial syndrome of Holstein calves, has been reported in aborted fetuses and in prematurely born, stillborn, and neonatal calves. Affected calves have anomalies in the vertebral column, including hemivertebrae, fused and misshapen vertebrae and ribs, scoliosis, and vertebral synostosis. Concurrent low body weight, symmetrical arthrogryposis, and cardiac anomalies have been documented in affected calves. The syndrome was identified and characterized in Holstein cattle in Denmark; however, a global distribution of this genetic disorder is likely based on identification of common ancestral sires widely used for artificial insemination. This is the first documented case of CVM in a Holstein calf in the USA.
ISSN:1040-6387
1943-4936
DOI:10.1177/104063870101300409