Antimicrobial activity of Argentine plants used in the treatment of infectious diseases. Isolation of active compounds from Sebastiania brasiliensis

Different extracts of Sebastiania brasiliensis, Sebastiania klotszchiana, Polygonum punctatum, Lithraea molleoides and Myrcianthes cisplatensis, all plants growing in Entre Rı́os Province and traditionally used as antiseptics, were tested against a set of Gram positive and Gram negative bacteria and...

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Bibliographic Details
Published in:Journal of ethnopharmacology 2001-09, Vol.77 (1), p.37-40
Main Authors: Penna, C, Marino, S, Vivot, E, Cruañes, M.C, de D. Muñoz, J, Cruañes, J, Ferraro, G, Gutkind, G, Martino, V
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - pharmacology
Antifungal Agents - pharmacology
Antimicrobial
Argentina
Biological and medical sciences
General pharmacology
Gram-Negative Bacteria - drug effects
Gram-Positive Bacteria - drug effects
Lithraea molleoides
Magnoliopsida - chemistry
Medical sciences
Methylgallate
Microbial Sensitivity Tests
Myrcianthes cisplatensis
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Phytotherapy
Plant Extracts - pharmacology
Plants, Medicinal
Polygonum punctatum
Protocatechuic acid
Sebastiania brasiliensis
Sebastiania klotszchiana
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Summary:Different extracts of Sebastiania brasiliensis, Sebastiania klotszchiana, Polygonum punctatum, Lithraea molleoides and Myrcianthes cisplatensis, all plants growing in Entre Rı́os Province and traditionally used as antiseptics, were tested against a set of Gram positive and Gram negative bacteria and fungi. All the species, with the exception of M. cisplatensis, presented activity against some of the microorganisms tested. A 50% hydroalcoholic extract of S. brasiliensis was selected for bioguided fractionation. Two antimicrobial compounds identified as methylgallate (MIC 128 μg/ml) and protocatechuic acid (MIC 128 μg/ml) were isolated apart from quercetin, kaempferol, quercitrin and gallic acid.
ISSN:0378-8741
1872-7573
DOI:10.1016/S0378-8741(01)00266-5