Synthesis and antimicrobial activity of ( E)-acetoxystilbenes and α,α′-dibromoacetoxybibenzyls

The synthesis of 13 new ( E)-acetoxystilbenes and α,α′-dibromoacetoxybibenzyls and their antimicrobial activity are reported. The results of microbiological screening of 17 ( E)-stilbenols and ( E)-acetoxystilbenes, unknown in the literature, have also been discussed. In particular, coumpounds 1c, 1...

Full description

Saved in:
Bibliographic Details
Published in:Farmaco (Società chimica italiana : 1989) 2000-02, Vol.55 (2), p.151-157
Main Authors: Wyrzykiewicz, Elżbieta, Błaszczyk, Alfred, Kędzia, Bogdan
Format: Article
Language:English
Subjects:
( E)-Acetoxystilbenes
Anti-Infective Agents - chemical synthesis
Anti-Infective Agents - chemistry
Anti-Infective Agents - pharmacology
Antibacterial agents
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antimicrobial activity
Bibenzyls - chemical synthesis
Bibenzyls - chemistry
Bibenzyls - pharmacology
Biological and medical sciences
Medical sciences
Microbial Sensitivity Tests
Pharmacology. Drug treatments
Stilbenes - chemical synthesis
Stilbenes - chemistry
Stilbenes - pharmacology
Structure-Activity Relationship
α,α′-Dibromoacetoxybibenzyls
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The synthesis of 13 new ( E)-acetoxystilbenes and α,α′-dibromoacetoxybibenzyls and their antimicrobial activity are reported. The results of microbiological screening of 17 ( E)-stilbenols and ( E)-acetoxystilbenes, unknown in the literature, have also been discussed. In particular, coumpounds 1c, 1g, 2a, 3a, 3b, 4a, 6a, 6b showed good antibacterial activity against Staphylococcus aureus and 1c also against Bacillus subtilis.
ISSN:0014-827X
1879-0569
DOI:10.1016/S0014-827X(99)00127-5