Dendritic cells and their role in skin-induced immune responses

This article gives a brief review on dendritic cells (DC) with regard to their origin, life cycle and functions. The regulation of immune responses by DC functioning as antigen‐presenting cells is discussed. Special attention is given to epidermal DC, e.g. Langerhans cells. The perspectives of DC‐ba...

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Bibliographic Details
Published in:Journal of the European Academy of Dermatology and Venereology 2001-03, Vol.15 (2), p.116-120
Main Authors: Holíková, Z, Hercogová, J, Plzák, J, Smetana Jr, K
Format: Article
Language:English
Subjects:
antigen presenting cell
Cell Cycle - immunology
dendritic cell
Dendritic Cells - immunology
Dendritic Cells - pathology
differentiation
Humans
Immune System - physiology
Langerhans cell
Sensitivity and Specificity
Skin - immunology
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Summary:This article gives a brief review on dendritic cells (DC) with regard to their origin, life cycle and functions. The regulation of immune responses by DC functioning as antigen‐presenting cells is discussed. Special attention is given to epidermal DC, e.g. Langerhans cells. The perspectives of DC‐based therapy are also mentioned.
ISSN:0926-9959
1468-3083
DOI:10.1046/j.1468-3083.2001.00225.x