Non-linear electroencephalogram dynamics in patients with spontaneous nocturnal migraine attacks

• Published in: Neuroscience letters 2001-08, Vol.309 (2), p.105-108
• Main Authors: Strenge, Hans, Fritzer, Gunther, Göder, Robert, Niederberger, Uwe, Gerber, Wolf-Dieter, Aldenhoff, Josef
• Format: Article
• Language: English
• Subjects: Attack; Biological and medical sciences; Correlation dimension; Electroencephalogram; Electroencephalography; Humans; Medical sciences; Migraine without aura; Migraine without Aura - diagnosis; Migraine without Aura - physiopathology; Neurology; Nonlinear Dynamics; Sleep; Sleep Stages; Vascular diseases and vascular malformations of the nervous system
• ISSN: 0304-3940; 1872-7972
• DOI: 10.1016/S0304-3940(01)02047-X

The present study was conducted to examine non-linear electroencephalogram (EEG) measures during the development of a spontaneous migraine attack. We investigated the sleep EEG of five patients with migraine without aura in the pain-free interval and at the onset of a nocturnal attack. Sleep EEG recordings were analysed using the method of global dimensional complexity compared to conventional sleep scoring techniques. We found no divergence between classical sleep architecture and the estimated dimensional course nor any relevant short-term changes related to the onset of headache. There was, however, a loss of dimensional complexity in the first two non-rapid eye movement sleep states in the migraine night, with statistical significance during the second sleep cycle. For the first time, these results provide evidence of a global dimension decrease that is related to cortical network changes during a migraine attack.