Increased serum arginase activity in depressed patients

1. 1. Arginase, an important part of the arginine-regulating system modulates nitric oxide generation; a neuroregulatory agent, which has been implicated in various neuropathological conditions. 2. 2. In this regard, the authors investigated the arginine-nitric oxide pathway by measuring serum argin...

Full description

Saved in:
Bibliographic Details
Published in:Progress in neuro-psychopharmacology & biological psychiatry 2000-02, Vol.24 (2), p.227-232
Main Authors: Elgün, Serenay, Kumbasar, Hakan
Format: Article
Language:English
Subjects:
Adult
Adult and adolescent clinical studies
arginase
Arginase - blood
Biological and medical sciences
Biomarkers - analysis
Depression
Depressive Disorder - enzymology
Depressive Disorder - physiopathology
Female
Humans
Male
Medical sciences
Middle Aged
Mood disorders
Nitric Oxide - metabolism
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
serum
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:1. 1. Arginase, an important part of the arginine-regulating system modulates nitric oxide generation; a neuroregulatory agent, which has been implicated in various neuropathological conditions. 2. 2. In this regard, the authors investigated the arginine-nitric oxide pathway by measuring serum arginase activity in drug free major ( n=18) and minor depressed outpatients ( n=12) and healthy control subjects ( n=30) in order to make a contribution to the understanding of disease mechanism. 3. 3. Major depressed patients were found to have significantly higher serum arginase activity compared to controls (p
ISSN:0278-5846
1878-4216
DOI:10.1016/S0278-5846(99)00100-1