Four-year follow-up study of sertraline and fluvoxamine in long-term treatment of unipolar subjects with high recurrence rate

We prolonged from 24 to 48 months a follow-up study of unipolar subjects with high recurrence rate treated with fluvoxamine ( N=25) and sertraline ( N=22). During the two-year additional period a significant risk of recurrences was observed during the third year of follow-up, without differences in...

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Bibliographic Details
Published in:Journal of affective disorders 2000-06, Vol.58 (3), p.233-236
Main Authors: Franchini, Linda, Gasperini, Mariangela, Zanardi, Raffaella, Smeraldi, Enrico
Format: Article
Language:English
Subjects:
Adult
Antidepressive Agents - therapeutic use
Antidepressive Agents, Second-Generation - therapeutic use
Depression
Depressive Disorder - drug therapy
Female
Fluvoxamine - therapeutic use
Follow-Up Studies
High recurrence
Humans
Long-term treatment
Male
Middle Aged
Recurrence
Sertraline - therapeutic use
SSRIs
Treatment Outcome
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Summary:We prolonged from 24 to 48 months a follow-up study of unipolar subjects with high recurrence rate treated with fluvoxamine ( N=25) and sertraline ( N=22). During the two-year additional period a significant risk of recurrences was observed during the third year of follow-up, without differences in the two long-term therapy groups. During the fourth year no patients showed new episodes of illness.
ISSN:0165-0327
1573-2517
DOI:10.1016/S0165-0327(99)00113-5