Myoepithelioma arising from the buccal gland : Histopathological and immunohistochemical studies

A rare case of myoepithelioma of the buccal gland in a 54-year-old Japanese woman is reported. As the swelling exhibited a normal mucosal color and was relatively well defined, showing no ulcers, a benign salivary gland tumor was suspected upon clinical inspection. Microscopically, the parenchyma of...

Full description

Saved in:
Bibliographic Details
Published in:Journal of Oral Science 2000, Vol.42(1), pp.39-42
Main Authors: Sugiura, Rie, Kuyama, Kayo, Utsunomiya, Tadahiko, Morikawa, Miyuki, Fukumoto, Masahiko, Yamamoto, Hirotsugu
Format: Article
Language:English
Subjects:
buccal gland
Cheek
Dentistry
Female
Humans
immunohistochemical study
Middle Aged
myoepithelioma
Myoepithelioma - chemistry
Myoepithelioma - pathology
Salivary Gland Neoplasms - chemistry
Salivary Gland Neoplasms - pathology
Salivary Glands, Minor - chemistry
Salivary Glands, Minor - pathology
Vimentin - analysis
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A rare case of myoepithelioma of the buccal gland in a 54-year-old Japanese woman is reported. As the swelling exhibited a normal mucosal color and was relatively well defined, showing no ulcers, a benign salivary gland tumor was suspected upon clinical inspection. Microscopically, the parenchyma of the present case mainly consisted of plasmacytoid cells with round nuclei and eosinophilic cytoplasm, and partial spindle cells with eccentric nuclei. The stroma was composed of fibro-hyalinized or myxoid connective tissue that separated from the parenchyma. Immunohistochemically, the cytoplasm of the plasmacytoid and spindle cells was moderately positive for vimentin and GFAP, whereas the buccal gland adjacent to the tumor was negative for these antibodies. S-100 protein reactivity is strong for both types tumor cells. Actin reactivity was negative for both types of tumor cells, notwithstanding the fact that myoepithelial cells of the buccal gland were positively stained. Anticytokeratin reactivity was weak for both types of tumor cells in portions of the plexiform and solid areas; nevertheless, the buccal glands were moderately positive.These results suggest that neoplasmic myoepithelial cells exhibit abnormal differentiation and modification. There have been only two published reports of myoepithelioma arising from the buccal gland in the literature to date. (J. Oral Sci.42, 39-42, 2000)
ISSN:1343-4934
1880-4926
DOI:10.2334/josnusd.42.39