Gastrointestinal stromal tumor of the duodenal ampulla: report of a case

We report herein the case of a 77-year-old woman with a gastrointestinal stromal tumor (GIST) of the duodenal ampulla. The tumor, which was removed by pancreatoduodenectomy due to its malignant potential, showed expansive growth in the muscular coat of the duodenal ampulla. Histologically, the tumor...

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Bibliographic Details
Published in:Surgery today (Tokyo, Japan) Japan), 2001-01, Vol.31 (8), p.722-726
Main Authors: Takahashi, Y, Noguchi, T, Takeno, S, Uchida, Y, Shimoda, H, Yokoyama, S
Format: Article
Language:English
Subjects:
Aged
Ampulla of Vater
Common Bile Duct Neoplasms - pathology
Common Bile Duct Neoplasms - surgery
Female
Gastrointestinal Neoplasms
Humans
Mesenchymoma - pathology
Mesenchymoma - surgery
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Summary:We report herein the case of a 77-year-old woman with a gastrointestinal stromal tumor (GIST) of the duodenal ampulla. The tumor, which was removed by pancreatoduodenectomy due to its malignant potential, showed expansive growth in the muscular coat of the duodenal ampulla. Histologically, the tumor cells were spindle-shaped or round, and exhibited fascicular or storiform growth pattern with frequent mitotic figures. The immunohistochemical and ultrastructural results suggested that the tumor may have originated from the interstitial cells of Cajal in the muscular coat of the duodenal ampulla. To our knowledge, this is the first case of malignant GIST of the duodenal ampulla to be reported in Japan.
ISSN:0941-1291
1436-2813
DOI:10.1007/s005950170079