The concentrations of osteocalcin and degradation products of type I collagen in pregnant women with pre-eclampsia

Objectives: To investigate the concentrations of osteocalcin and collagen type I C-terminal telopeptides in pregnant women with pre-eclampsia. Study design: 26 patients with severe pre-eclampsia and 24 healthy pregnant women were included in the study. Serum concentrations of osteocalcin and C-telop...

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Published in:European journal of obstetrics & gynecology and reproductive biology 2001-09, Vol.98 (1), p.23-27
Main Authors: Gorzelak, Mieczyslaw, Darmochwal-Kolarz, Dorota, Jablonski, Miroslaw, Rolinski, Jacek, Leszczynska-Gorzelak, Bozena, Modrzewski, Krzysztof, Oleszczuk, Jan
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Bone and Bones - metabolism
Collagen - blood
Collagen Type I
Collagen type I C-terminal telopeptides
Diseases of mother, fetus and pregnancy
Enzyme-Linked Immunosorbent Assay
Female
Gynecology. Andrology. Obstetrics
Humans
Medical sciences
Osteocalcin
Osteocalcin - blood
Peptides - blood
Pre-eclampsia
Pre-Eclampsia - blood
Pregnancy
Pregnancy. Fetus. Placenta
Reference Values
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Summary:Objectives: To investigate the concentrations of osteocalcin and collagen type I C-terminal telopeptides in pregnant women with pre-eclampsia. Study design: 26 patients with severe pre-eclampsia and 24 healthy pregnant women were included in the study. Serum concentrations of osteocalcin and C-telopeptides — degradation products of type I collagen were determined using the ELISA method. Statistical analysis was performed using Mann–Whitney U-test. Results: In pre-eclamptic patients, the concentrations of osteocalcin and degradation products of collagen type I were significantly higher ( P
ISSN:0301-2115
1872-7654
DOI:10.1016/S0301-2115(01)00319-0