Packaged merozoite release without immediate host cell lysis

In spite of the extraordinary progress in unravelling the genome of the Plasmodium falciparum parasite, many crucial aspects of its biology remain poorly understood. One largely neglected area is the mechanism of merozoite release from host red blood cells.

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Bibliographic Details
Published in:Trends in parasitology 2001-09, Vol.17 (9), p.401-403
Main Author: Lew, Virgilio L.
Format: Article
Language:English
Subjects:
Animals
Erythrocyte Membrane - physiology
Erythrocytes - parasitology
Erythrocytes - physiology
haemolysis
Hemolysis
Humans
Malaria, Falciparum - parasitology
Membrane Fusion
merozoite release
parasitophorous vacuolar memebrance
Plasmodium falciparum
Plasmodium falciparum - physiology
proteases
red blood cells
Vacuoles - physiology
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Description
Summary:In spite of the extraordinary progress in unravelling the genome of the Plasmodium falciparum parasite, many crucial aspects of its biology remain poorly understood. One largely neglected area is the mechanism of merozoite release from host red blood cells.
ISSN:1471-4922
1471-5007
DOI:10.1016/S1471-4922(01)02055-4