Effectiveness of statins in acute coronary syndromes

Over the past several years, results of clinical trials of lipid lowering have increased our understanding of the pathophysiology of coronary atherosclerosis and ischemia. Evidence is accumulating that cholesterol lowering has potential anti-ischemic effects and may have immediate consequences that...

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Bibliographic Details
Published in:The American journal of cardiology 2001-08, Vol.88 (4), p.31-35
Main Authors: Foody, JoAnne Micale, Nissen, Steven E.
Format: Article
Language:English
Subjects:
Acute Disease
Anticholesteremic Agents - therapeutic use
Biological and medical sciences
Cardiovascular disease
Cholesterol
Cholesterol, LDL - blood
Clinical trials
Coronary Artery Disease - drug therapy
Coronary vessels
General and cellular metabolism. Vitamins
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use
Hypercholesterolemia - drug therapy
Hypolipidemic Agents - therapeutic use
Lipids
Medical research
Medical sciences
Myocardial Ischemia - prevention & control
Pharmacology. Drug treatments
Randomized Controlled Trials as Topic
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Summary:Over the past several years, results of clinical trials of lipid lowering have increased our understanding of the pathophysiology of coronary atherosclerosis and ischemia. Evidence is accumulating that cholesterol lowering has potential anti-ischemic effects and may have immediate consequences that have a favorable impact on coronary events, possibly even acute coronary syndromes. Yet, less than one half of all patients hospitalized for acute coronary syndromes have their cardiovascular risks appropriately modified. The results of recent statin trials provide impetus for the implementation of aggressive risk-reduction strategies in patients with coronary atherosclerosis, including those with recent acute coronary syndromes. Prevention is now a viable therapeutic goal.
ISSN:0002-9149
1879-1913
DOI:10.1016/S0002-9149(01)01875-6