Epithelioid blue nevus: a rare variant of blue nevus not always associated with the Carney complex

Epithelioid blue nevus is a rare variant of blue nevus that has been recently described in patients with Carney complex. Some of the patients with Carney complex have multiple epithelioid blue nevi and a familial history of similar lesions is often recorded. Epithelioid blue nevus consists of an int...

Full description

Saved in:
Bibliographic Details
Published in:Journal of cutaneous pathology 2000-05, Vol.27 (5), p.218-223
Main Authors: Moreno, Carmen, Requena, Luis, Kutzner, Heinz, De La Cruz, Alberto, Jaqueti, Gerardo, Yus, Evaristo Sánchez
Format: Article
Language:English
Subjects:
Adult
Antigens, Neoplasm
Biological and medical sciences
Biomarkers, Tumor - analysis
Dermatology
Female
Humans
Immunohistochemistry
Male
MART-1 Antigen
Medical sciences
Middle Aged
Neoplasm Proteins - analysis
Neoplastic Syndromes, Hereditary - complications
Neoplastic Syndromes, Hereditary - pathology
Nevus, Blue - chemistry
Nevus, Blue - complications
Nevus, Blue - pathology
Nevus, Blue - surgery
Nevus, Epithelioid and Spindle Cell - chemistry
Nevus, Epithelioid and Spindle Cell - complications
Nevus, Epithelioid and Spindle Cell - pathology
Nevus, Epithelioid and Spindle Cell - surgery
Skin Neoplasms - chemistry
Skin Neoplasms - complications
Skin Neoplasms - pathology
Skin Neoplasms - surgery
Tumors of the skin and soft tissue. Premalignant lesions
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Epithelioid blue nevus is a rare variant of blue nevus that has been recently described in patients with Carney complex. Some of the patients with Carney complex have multiple epithelioid blue nevi and a familial history of similar lesions is often recorded. Epithelioid blue nevus consists of an intradermal melanocytic nevus composed of polygonal epithelioid cells laden with melanin. Neoplastic cells show no maturation at the base of the lesion and, in contrast with the usual stromal changes in blue nevi, epithelioid blue nevus exhibits no fibrosis of the dermis. We have studied three cases of epithelioid blue nevus in three patients with no evidence of Carney complex. The lesions were solitary and there was no family history of similar lesions. Therefore, epithelioid blue nevus is a distinctive variant of blue nevus that may also appear as a sporadic lesion and is not always associated with Carney complex.
ISSN:0303-6987
1600-0560
DOI:10.1034/j.1600-0560.2000.027005218.x