Primary intrathoracic meningioma: histopathological, immunohistochemical and ultrastructural study of two cases

Meningiomas are common, usually benign slow-growing neoplasms of the central nervous system thought to arise from meningocytes capping arachnoid villi. Primary ectopic meningiomas are exceedingly rare extracranial and extraspinal tumors of controversial origin; they are usually limited to the head a...

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Bibliographic Details
Published in:Virchows Archiv : an international journal of pathology 2001-08, Vol.439 (2), p.196-200
Main Authors: FALLENI, Monica, ROZ, Elena, DESSY, Enrico, DEL CURTO, Barbara, BRAIDOTTI, Paola, GIANELLI, Umberto, PIETRA, Giuseppe G
Format: Article
Language:English
Subjects:
Biological and medical sciences
Biomarkers, Tumor - analysis
Diagnosis, Differential
Female
Humans
Immunoenzyme Techniques
Lung Neoplasms - chemistry
Lung Neoplasms - pathology
Lung Neoplasms - surgery
Male
Mediastinal Neoplasms - chemistry
Mediastinal Neoplasms - pathology
Mediastinal Neoplasms - surgery
Medical sciences
Melanoma - diagnosis
Melanoma - secondary
Meningioma - chemistry
Meningioma - pathology
Meningioma - surgery
Middle Aged
Neoplasms, Muscle Tissue - diagnosis
Peripheral Nervous System Neoplasms - diagnosis
Pneumology
Treatment Outcome
Tumors of the respiratory system and mediastinum
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Description
Summary:Meningiomas are common, usually benign slow-growing neoplasms of the central nervous system thought to arise from meningocytes capping arachnoid villi. Primary ectopic meningiomas are exceedingly rare extracranial and extraspinal tumors of controversial origin; they are usually limited to the head and neck region or to the paravertebral soft tissues. Only one mediastinal ectopic meningioma and few pulmonary ectopic meningiomas have been described in the literature until now. Because of their rarity and their intriguing pathogenesis, we report here a second case of primary mediastinal meningioma and an additional case of primary pulmonary meningioma. Their possible origin and differential diagnosis are discussed.
ISSN:0945-6317
1432-2307
DOI:10.1007/s004280000387