Tailed nuclei and dicentric chromosomes in irradiated subjects

A study of peripheral blood smears from irradiated Chernobyl liquidators and other subjects has shown nuclei of some lymphocytes to have a protrusion into the cytoplasm. Such abnormal nuclei are called “tailed” nuclei (TN). Sixteen main morphologic types, observed in human peripheral blood lymphocyt...

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Bibliographic Details
Published in:Applied radiation and isotopes 2000-05, Vol.52 (5), p.1121-1127
Main Authors: Kravtsov, V.Yu, Fedortseva, R.F, Starkova, Ye.V, Yartseva, N.M, Nikiforov, A.M
Format: Article
Language:English
Subjects:
Adult
Aged
Cell Nucleus - radiation effects
Cell Nucleus - ultrastructure
Chromosome Aberrations
Chromosomes, Human - radiation effects
Chromosomes, Human - ultrastructure
Humans
Lymphocytes - radiation effects
Lymphocytes - ultrastructure
Male
Middle Aged
Radioactive Hazard Release
Ukraine
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Summary:A study of peripheral blood smears from irradiated Chernobyl liquidators and other subjects has shown nuclei of some lymphocytes to have a protrusion into the cytoplasm. Such abnormal nuclei are called “tailed” nuclei (TN). Sixteen main morphologic types, observed in human peripheral blood lymphocytes, are described. The frequency of appearance of lymphocytes with TN in a group of Chernobyl liquidators was significantly higher than in control groups ( p
ISSN:0969-8043
1872-9800
DOI:10.1016/S0969-8043(00)00057-9