Disseminated cutaneous infection with Mycobacterium kansasii: Genotyping versus phenotyping

Mycobacterium kansasii is a common and virulent pathogen. However, primary cutaneous M kansasii infection has rarely been reported, totaling to only 34 cases since 1965. This low incidence has not been explained, but probably is due to difficulty in culture or phenotyping. We describe the first repo...

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Bibliographic Details
Published in:Journal of the American Academy of Dermatology 2001-10, Vol.45 (4), p.620-624
Main Authors: Tzen, Chin-Yuan, Chen, Tien-Ling, Wu, Tsu-Yen, Yong, Dine-Ie, Lee, Huei-Chung
Format: Article
Language:English
Subjects:
Adult
Bacterial diseases
Biological and medical sciences
DNA, Bacterial - genetics
Female
Genotype
Human bacterial diseases
Humans
Infectious diseases
Medical sciences
Mycobacterium Infections, Nontuberculous - pathology
Mycobacterium kansasii - genetics
Mycobacterium kansasii - pathogenicity
Phenotype
Polymerase Chain Reaction
Tropical medicine
Tuberculosis and atypical mycobacterial infections
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Summary:Mycobacterium kansasii is a common and virulent pathogen. However, primary cutaneous M kansasii infection has rarely been reported, totaling to only 34 cases since 1965. This low incidence has not been explained, but probably is due to difficulty in culture or phenotyping. We describe the first reported case of cutaneous M kansasii diagnosed by genotyping, which is based on the DNA extracted from the formalin-fixed and paraffin-embedded tissue. (J Am Acad Dermatol 2001;45:620-4.)
ISSN:0190-9622
1097-6787
DOI:10.1067/mjd.2001.114745