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Are outcomes of surgical versus transcatheter balloon valvotomy equivalent in neonatal critical aortic stenosis?

For neonates with critical aortic valve stenosis who are selected for biventricular repair, valvotomy can be achieved surgically (SAV) or by transcatheter balloon dilation (BAV). Data regarding 110 neonates with critical aortic valve stenosis were evaluated in a study by the Congenital Heart Surgeon...

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Published in:Circulation (New York, N.Y.) N.Y.), 2001-09, Vol.104 (12 Suppl 1), p.I152-I158
Main Authors: McCrindle, B W, Blackstone, E H, Williams, W G, Sittiwangkul, R, Spray, T L, Azakie, A, Jonas, R A
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container_title Circulation (New York, N.Y.)
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creator McCrindle, B W
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description For neonates with critical aortic valve stenosis who are selected for biventricular repair, valvotomy can be achieved surgically (SAV) or by transcatheter balloon dilation (BAV). Data regarding 110 neonates with critical aortic valve stenosis were evaluated in a study by the Congenital Heart Surgeons Society from 1994 to 1999. Reduced left ventricular function was present in 46% of neonates. The initial procedure was SAV in 28 patients and BAV in 82 patients. Mean percent reduction in systolic gradient was significantly greater with BAV (65+/-17%) than SAV (41+/-32%; P
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Data regarding 110 neonates with critical aortic valve stenosis were evaluated in a study by the Congenital Heart Surgeons Society from 1994 to 1999. Reduced left ventricular function was present in 46% of neonates. The initial procedure was SAV in 28 patients and BAV in 82 patients. Mean percent reduction in systolic gradient was significantly greater with BAV (65+/-17%) than SAV (41+/-32%; P&lt;0.001). Higher residual median gradients were present in the SAV versus BAV group (36 mm Hg [range, 10 to 85 mm Hg] versus 20 mm Hg [0 to 85 mm Hg], P&lt;0.001). Important aortic regurgitation was more often present after BAV (18%) than SAV (3%; P=0.07). Time-related survival after valvotomy was 82% at 1 month and 72% at 5 years, with no significant difference for SAV versus BAV, even after adjustment for differences in patient and disease characteristics. Independent risk factors for mortality were mechanical ventilation before valvotomy, smaller aortic valve annulus (z score), smaller aortic diameter at the sinotubular junction (z score), and a smaller subaortic region. A second procedure was performed in 46 survivors. Estimates for freedom from reintervention were 91% at 1 month and 48% at 5 years after the initial valvotomy and did not differ significantly between groups. SAV and BAV for neonatal critical aortic stenosis have similar outcomes. 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ispartof Circulation (New York, N.Y.), 2001-09, Vol.104 (12 Suppl 1), p.I152-I158
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source Free E-Journal (出版社公開部分のみ)
subjects Acute Disease
Aortic Valve Insufficiency - etiology
Aortic Valve Stenosis - diagnosis
Aortic Valve Stenosis - surgery
Cardiac Surgical Procedures - adverse effects
Cardiac Surgical Procedures - statistics & numerical data
Catheterization - statistics & numerical data
Demography
Echocardiography
Follow-Up Studies
Humans
Infant, Newborn
Prospective Studies
Reoperation - statistics & numerical data
Risk Assessment
Risk Factors
Survival Analysis
Survival Rate
Treatment Outcome
Videotape Recording
title Are outcomes of surgical versus transcatheter balloon valvotomy equivalent in neonatal critical aortic stenosis?
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