Cervical Cancer: Prevention, Diagnosis, and Therapeutics

Cervical cancer is a leading cause of cancer deaths in women worldwide. Because of its association with human papilloma virus infection, as well as the ability to screen for premalignant stages of the disease, it is now largely a preventable disease. This article describes the molecular basis for ce...

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Bibliographic Details
Published in:CA: a cancer journal for clinicians 2001-03, Vol.51 (2), p.92-114
Main Authors: Janicek, Mike F, Averette, Hervy E
Format: Article
Language:English
Subjects:
Cervical cancer
Female
Humans
Immune system
Medical diagnosis
Neoplasm Recurrence, Local
Neoplasm Staging
Papillomaviridae - classification
Papillomaviridae - isolation & purification
Prevention
Risk Factors
T-Lymphocytes, Cytotoxic - immunology
Uterine Cervical Neoplasms - diagnosis
Uterine Cervical Neoplasms - etiology
Uterine Cervical Neoplasms - therapy
Vaginal Smears
Viruses
Citations: Items that cite this one
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Description
Summary:Cervical cancer is a leading cause of cancer deaths in women worldwide. Because of its association with human papilloma virus infection, as well as the ability to screen for premalignant stages of the disease, it is now largely a preventable disease. This article describes the molecular basis for cervical cancer, and presents a clinical overview of current treatment approaches and technological advances, emphasizing the unique aspects of this viral disease as it relates to the immune system and vaccination or other immunotherapeutic strategies.
ISSN:0007-9235
1542-4863
DOI:10.3322/canjclin.51.2.92