The hormonal factors regulating water-electrolyte exchange in the pathogenesis of the hemodynamic disorders in pre-eclampsia

Study of indices of different endocrine links of female organisms with gestosis of the 2nd half of pregnancy with the search of degree of taking part of this hormones in the forming of basic syndromes of hestosis and guiding line to fundamental approach in medicinal practice with gestosis. Decrease...

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Bibliographic Details
Published in:Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) Ukraine : 1994), 2000, Vol.46 (2), p.48-54
Main Authors: Zaporozhan, V M, Hozhenko, A I, Svirs'kyĭ, O O, Zalins'kyĭ, O O
Format: Article
Language:Ukrainian
Subjects:
Adaptation, Physiological
Adult
Female
Hemodynamics - physiology
Humans
Natriuretic Agents - physiology
Pre-Eclampsia - etiology
Pre-Eclampsia - physiopathology
Pregnancy
Pregnancy Trimester, Third
Prostaglandins - physiology
Renin-Angiotensin System - physiology
Sodium - physiology
Water-Electrolyte Balance - physiology
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Summary:Study of indices of different endocrine links of female organisms with gestosis of the 2nd half of pregnancy with the search of degree of taking part of this hormones in the forming of basic syndromes of hestosis and guiding line to fundamental approach in medicinal practice with gestosis. Decrease of natrium content in CBV at the same time with decrease of intravascular volume of it and decrease of excretion of it with urine in the dynamics of gestosis confirms hestosis development and retention of natrium in the expectorant women's organism with primary delay of it in tissues. Energization of renin-angiotensin-aldosterone-tromboxane system, changes of prostaglandin-tromboxane link in blood contributed to forming of arterial hypertension and edema. With taking into account revealed changes of hormonal levels at the background of progressive hypovolemia, decrease of speed of excretion of natrium with urine and speed of glomerular filtration, differentiate approach in prescription for hypotensive and diuretic agents is recommended for the avoidance of possible hardening of state of expectorant woman with gestosis.
ISSN:2522-9028