Change of antimicrobial susceptibility of group B streptococci over 15 years in Japan

We compared antimicrobial susceptibility patterns of 206 group B streptococcal (GBS) strains isolated from pregnant women and six from neonates/infants with invasive infection during the two periods 1985–1986 and 1999–2000. All strains in both periods were susceptible to the penicillins, cephalospor...

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Bibliographic Details
Published in:Journal of antimicrobial chemotherapy 2001-10, Vol.48 (4), p.579-582
Main Authors: Matsubara, Kousaku, Nishiyama, Yasunobu, Katayama, Kazuaki, Yamamoto, Gou, Sugiyama, Masako, Murai, Teiko, Baba, Kunizo
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - pharmacology
Antibacterial agents
Antibiotics. Antiinfectious agents. Antiparasitic agents
Biological and medical sciences
Drug Resistance, Bacterial
Female
Humans
Infant, Newborn
Infectious Disease Transmission, Vertical - prevention & control
Japan - epidemiology
Lactams
Medical sciences
Microbial Sensitivity Tests
Pharmacology. Drug treatments
Pregnancy
Pregnancy Complications, Infectious - epidemiology
Pregnancy Complications, Infectious - microbiology
Serotyping
Streptococcal Infections - epidemiology
Streptococcal Infections - microbiology
Streptococcus agalactiae - classification
Streptococcus agalactiae - drug effects
Time Factors
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Summary:We compared antimicrobial susceptibility patterns of 206 group B streptococcal (GBS) strains isolated from pregnant women and six from neonates/infants with invasive infection during the two periods 1985–1986 and 1999–2000. All strains in both periods were susceptible to the penicillins, cephalosporins and carbapenem tested. Seven (3%) isolates were resistant to erythromycin and three (1%) were resistant to clindamycin. There were no significant differences between the two study periods in the incidence of GBS resistant to the 14 antibiotics tested. These results showed that penicillins are still the first choice to prevent vertical transmission of GBS in Japan.
ISSN:0305-7453
1460-2091
1460-2091
DOI:10.1093/jac/48.4.579