The Strengthening Effect of Percutaneous Vertebroplasty
AIM: To examine whether single-needle vertebroplasty is effective in strengthening vertebrae. MATERIALS AND METHODS: Four adjacent intact lumbar vertebrae were removed from each of nine adult post-mortem subjects. One or two vertebra of each set was injected with low viscosity acrylic bone cement us...
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| Published in: | Clinical radiology 2000-06, Vol.55 (6), p.471-476 |
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| container_end_page | 476 |
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| container_title | Clinical radiology |
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| creator | DEAN, J.R. ISON, K.T. GISHEN, P. |
| description | AIM: To examine whether single-needle vertebroplasty is effective in strengthening vertebrae.
MATERIALS AND METHODS: Four adjacent intact lumbar vertebrae were removed from each of nine adult post-mortem subjects. One or two vertebra of each set was injected with low viscosity acrylic bone cement using a single-track posterolateral approach. Vertebral strength was measured during constant rate axial compression.
RESULTS: Single-needle injection delivered different quantities of cement (1–8ml) in an asymmetric distribution. Injected vertebrae were stronger than controls in 10 out of 12 cases (P |
| doi_str_mv | 10.1053/crad.2000.0478 |
| format | article |
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MATERIALS AND METHODS: Four adjacent intact lumbar vertebrae were removed from each of nine adult post-mortem subjects. One or two vertebra of each set was injected with low viscosity acrylic bone cement using a single-track posterolateral approach. Vertebral strength was measured during constant rate axial compression.
RESULTS: Single-needle injection delivered different quantities of cement (1–8ml) in an asymmetric distribution. Injected vertebrae were stronger than controls in 10 out of 12 cases (P<0.01), suggesting that cement injection increases the load needed to cause initial vertebral fracture. Compression was continued past the point of initial failure, to simulate progressive vertebral collapse. Injected specimens were more resistant to deformation than control specimens (P<0.05), most of which initially deformed with little increase in load.
CONCLUSION: Single-track injection of bone cement appeared to strengthen vertebrae against both initial failure and subsequent collapse. The magnitude of strength increase from vertebroplasty was variable, and did not correlate with the volume of cement injected. Further investigation is needed to optimize the technique.Gishen, P. (2000). Clinical Radiology55, 471–476.</description><identifier>ISSN: 0009-9260</identifier><identifier>EISSN: 1365-229X</identifier><identifier>DOI: 10.1053/crad.2000.0478</identifier><identifier>PMID: 10873694</identifier><identifier>CODEN: CLRAAG</identifier><language>eng</language><publisher>Amsterdam: Elsevier Ltd</publisher><subject>Aged ; Aged, 80 and over ; Biological and medical sciences ; Biomechanical Phenomena ; Bone Cements - therapeutic use ; Compressive Strength - drug effects ; Diseases of the osteoarticular system ; Diseases of the spine ; Dose-Response Relationship, Drug ; Female ; Humans ; Investigative techniques, diagnostic techniques (general aspects) ; Lumbar Vertebrae - diagnostic imaging ; Lumbar Vertebrae - drug effects ; Lumbar Vertebrae - physiology ; Male ; Medical sciences ; Middle Aged ; Osteoarticular system. Muscles ; Polymethyl Methacrylate - therapeutic use ; Radiodiagnosis. Nmr imagery. Nmr spectrometry ; Radiography ; Statistics, Nonparametric ; vertebroplasty, bone cement, methyl methacrylate, lumbar spine</subject><ispartof>Clinical radiology, 2000-06, Vol.55 (6), p.471-476</ispartof><rights>2000 The Royal College of Radiologists</rights><rights>2000 INIST-CNRS</rights><rights>Copyright 2000 The Royal College of Radiologists.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c435t-1231f43d6d1b1aa0374305a32648c9ba5a9479b037da288bc178aa8101b44c203</citedby><cites>FETCH-LOGICAL-c435t-1231f43d6d1b1aa0374305a32648c9ba5a9479b037da288bc178aa8101b44c203</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27898,27899</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1389191$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10873694$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>DEAN, J.R.</creatorcontrib><creatorcontrib>ISON, K.T.</creatorcontrib><creatorcontrib>GISHEN, P.</creatorcontrib><title>The Strengthening Effect of Percutaneous Vertebroplasty</title><title>Clinical radiology</title><addtitle>Clin Radiol</addtitle><description>AIM: To examine whether single-needle vertebroplasty is effective in strengthening vertebrae.
MATERIALS AND METHODS: Four adjacent intact lumbar vertebrae were removed from each of nine adult post-mortem subjects. One or two vertebra of each set was injected with low viscosity acrylic bone cement using a single-track posterolateral approach. Vertebral strength was measured during constant rate axial compression.
RESULTS: Single-needle injection delivered different quantities of cement (1–8ml) in an asymmetric distribution. Injected vertebrae were stronger than controls in 10 out of 12 cases (P<0.01), suggesting that cement injection increases the load needed to cause initial vertebral fracture. Compression was continued past the point of initial failure, to simulate progressive vertebral collapse. Injected specimens were more resistant to deformation than control specimens (P<0.05), most of which initially deformed with little increase in load.
CONCLUSION: Single-track injection of bone cement appeared to strengthen vertebrae against both initial failure and subsequent collapse. The magnitude of strength increase from vertebroplasty was variable, and did not correlate with the volume of cement injected. Further investigation is needed to optimize the technique.Gishen, P. (2000). Clinical Radiology55, 471–476.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biological and medical sciences</subject><subject>Biomechanical Phenomena</subject><subject>Bone Cements - therapeutic use</subject><subject>Compressive Strength - drug effects</subject><subject>Diseases of the osteoarticular system</subject><subject>Diseases of the spine</subject><subject>Dose-Response Relationship, Drug</subject><subject>Female</subject><subject>Humans</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Lumbar Vertebrae - diagnostic imaging</subject><subject>Lumbar Vertebrae - drug effects</subject><subject>Lumbar Vertebrae - physiology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Osteoarticular system. Muscles</subject><subject>Polymethyl Methacrylate - therapeutic use</subject><subject>Radiodiagnosis. Nmr imagery. Nmr spectrometry</subject><subject>Radiography</subject><subject>Statistics, Nonparametric</subject><subject>vertebroplasty, bone cement, methyl methacrylate, lumbar spine</subject><issn>0009-9260</issn><issn>1365-229X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><recordid>eNp1kE1Lw0AQhhdRbK1ePUoO4i1xZ3eT7B6l1A8oKFjF27LZTNpImtTdROi_NyEFvXga5uWZl-Eh5BJoBDTmt9aZPGKU0oiKVB6RKfAkDhlTH8dk2scqVCyhE3Lm_eewCiZOyQSoTHmixJSkqw0Gr63Det1usC7rdbAoCrRt0BTBCzrbtabGpvPBO7oWM9fsKuPb_Tk5KUzl8eIwZ-TtfrGaP4bL54en-d0ytILHbQiMQyF4nuSQgTGUp4LT2HCWCGlVZmKjRKqyPs8NkzKzkEpjJFDIhLCM8hm5GXt3rvnq0Ld6W3qLVTV-pVNgIAWIHoxG0LrGe4eF3rlya9xeA9WDKj2o0oMqPajqD64OzV22xfwPPrrpgesDYLw1VeFMbUv_y3GpQEGPyRHDXsN3iU57W2JtMS9d71HnTfnfCz9HCoM5</recordid><startdate>20000601</startdate><enddate>20000601</enddate><creator>DEAN, J.R.</creator><creator>ISON, K.T.</creator><creator>GISHEN, P.</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20000601</creationdate><title>The Strengthening Effect of Percutaneous Vertebroplasty</title><author>DEAN, J.R. ; ISON, K.T. ; GISHEN, P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c435t-1231f43d6d1b1aa0374305a32648c9ba5a9479b037da288bc178aa8101b44c203</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biological and medical sciences</topic><topic>Biomechanical Phenomena</topic><topic>Bone Cements - therapeutic use</topic><topic>Compressive Strength - drug effects</topic><topic>Diseases of the osteoarticular system</topic><topic>Diseases of the spine</topic><topic>Dose-Response Relationship, Drug</topic><topic>Female</topic><topic>Humans</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Lumbar Vertebrae - diagnostic imaging</topic><topic>Lumbar Vertebrae - drug effects</topic><topic>Lumbar Vertebrae - physiology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Osteoarticular system. Muscles</topic><topic>Polymethyl Methacrylate - therapeutic use</topic><topic>Radiodiagnosis. Nmr imagery. Nmr spectrometry</topic><topic>Radiography</topic><topic>Statistics, Nonparametric</topic><topic>vertebroplasty, bone cement, methyl methacrylate, lumbar spine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>DEAN, J.R.</creatorcontrib><creatorcontrib>ISON, K.T.</creatorcontrib><creatorcontrib>GISHEN, P.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical radiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>DEAN, J.R.</au><au>ISON, K.T.</au><au>GISHEN, P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Strengthening Effect of Percutaneous Vertebroplasty</atitle><jtitle>Clinical radiology</jtitle><addtitle>Clin Radiol</addtitle><date>2000-06-01</date><risdate>2000</risdate><volume>55</volume><issue>6</issue><spage>471</spage><epage>476</epage><pages>471-476</pages><issn>0009-9260</issn><eissn>1365-229X</eissn><coden>CLRAAG</coden><abstract>AIM: To examine whether single-needle vertebroplasty is effective in strengthening vertebrae.
MATERIALS AND METHODS: Four adjacent intact lumbar vertebrae were removed from each of nine adult post-mortem subjects. One or two vertebra of each set was injected with low viscosity acrylic bone cement using a single-track posterolateral approach. Vertebral strength was measured during constant rate axial compression.
RESULTS: Single-needle injection delivered different quantities of cement (1–8ml) in an asymmetric distribution. Injected vertebrae were stronger than controls in 10 out of 12 cases (P<0.01), suggesting that cement injection increases the load needed to cause initial vertebral fracture. Compression was continued past the point of initial failure, to simulate progressive vertebral collapse. Injected specimens were more resistant to deformation than control specimens (P<0.05), most of which initially deformed with little increase in load.
CONCLUSION: Single-track injection of bone cement appeared to strengthen vertebrae against both initial failure and subsequent collapse. The magnitude of strength increase from vertebroplasty was variable, and did not correlate with the volume of cement injected. Further investigation is needed to optimize the technique.Gishen, P. (2000). Clinical Radiology55, 471–476.</abstract><cop>Amsterdam</cop><pub>Elsevier Ltd</pub><pmid>10873694</pmid><doi>10.1053/crad.2000.0478</doi><tpages>6</tpages></addata></record> |
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| subjects | Aged Aged, 80 and over Biological and medical sciences Biomechanical Phenomena Bone Cements - therapeutic use Compressive Strength - drug effects Diseases of the osteoarticular system Diseases of the spine Dose-Response Relationship, Drug Female Humans Investigative techniques, diagnostic techniques (general aspects) Lumbar Vertebrae - diagnostic imaging Lumbar Vertebrae - drug effects Lumbar Vertebrae - physiology Male Medical sciences Middle Aged Osteoarticular system. Muscles Polymethyl Methacrylate - therapeutic use Radiodiagnosis. Nmr imagery. Nmr spectrometry Radiography Statistics, Nonparametric vertebroplasty, bone cement, methyl methacrylate, lumbar spine |
| title | The Strengthening Effect of Percutaneous Vertebroplasty |
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