Thalamic changes with mesial temporal sclerosis: MRI

We reviewed the preoperative images of 28 patients with pathologically proven mesial temporal sclerosis, to assess thalamic asymmetry and signal change. A further 25 nonsurgical patients with temporal lobe epilepsy and unequivocal, unilateral changes of mesial temporal sclerosis, and 20 controls, we...

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Bibliographic Details
Published in:Neuroradiology 2000-05, Vol.42 (5), p.346-351
Main Authors: Deasy, N P, Jarosz, J M, Elwes, R C, Polkey, C E, Cox, T C
Format: Article
Language:English
Subjects:
Adult
Atrophy
Epilepsy, Temporal Lobe - complications
Epilepsy, Temporal Lobe - pathology
Female
Humans
Magnetic Resonance Imaging
Male
Sclerosis - pathology
Temporal Lobe - pathology
Thalamus - pathology
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Summary:We reviewed the preoperative images of 28 patients with pathologically proven mesial temporal sclerosis, to assess thalamic asymmetry and signal change. A further 25 nonsurgical patients with temporal lobe epilepsy and unequivocal, unilateral changes of mesial temporal sclerosis, and 20 controls, were also reviewed. None of the control group had unequivocal asymmetry of the thalamus. There was an ipsilateral asymmetrically small thalamus in five (18%) of the surgical group and in three (12%) of the nonsurgical patients. In four cases there was thalamic signal change. In three patients with thalamic volume loss there was ipsilateral hemiatrophy. All patients with an asymmetrically small thalamus had an asymmetrically small fornix and all but one a small ipsilateral mamillary body.
ISSN:0028-3940
1432-1920
DOI:10.1007/s002340050896