Brain Tumors as Second Malignant Neoplasms in Patients with Osteosarcoma Treated with Adjuvant and Neoadjuvant Chemotherapy: Report of 2 Cases

A malignant, primary brain tumor developed as Second Malignant Neoplasm (SMN) in 2/490 long-term-survivor osteosarcoma patients treated at our Institute over a 20-yr period. They developed the brain tumor (one astrocytoma and one glioblastoma) 3 and 5 yr after treatment, (chemotherapy and surgery),...

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Bibliographic Details
Published in:Journal of chemotherapy (Florence) 2000-06, Vol.12 (3), p.261-262
Main Authors: Longhi, A., Gamberi, G., Bacci, G.
Format: Article
Language:English
Subjects:
Adult
Astrocytoma
Biological and medical sciences
Bone Neoplasms - drug therapy
Bone Neoplasms - surgery
Bone Neoplasms - therapy
Brain Neoplasms
Chemotherapy, Adjuvant
Diseases of the osteoarticular system
Glioblastoma
Humans
Male
Medical sciences
Neoplasms, Second Primary
Neurology
Osteosarcoma - drug therapy
Osteosarcoma - surgery
Osteosarcoma - therapy
Tumors of striated muscle and skeleton
Tumors of the nervous system. Phacomatoses
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Summary:A malignant, primary brain tumor developed as Second Malignant Neoplasm (SMN) in 2/490 long-term-survivor osteosarcoma patients treated at our Institute over a 20-yr period. They developed the brain tumor (one astrocytoma and one glioblastoma) 3 and 5 yr after treatment, (chemotherapy and surgery), for localized osteosarcoma of the extremity.
ISSN:1120-009X
1973-9478
DOI:10.1179/joc.2000.12.3.261