The place of antibiotic therapy in the management of chronic acute exacerbations of chronic bronchitis

In the USA, more than 16 million adults are affected by chronic obstructive pulmonary disease, and chronic bronchitis has been estimated to affect up to 13 million individuals or approximately 4–6% of adults. Chronic bronchitis is an increasing cause of significant morbidity and mortality. During ac...

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Bibliographic Details
Published in:International journal of antimicrobial agents 2001-01, Vol.18, p.49-55
Main Author: Akalin, H.E.
Format: Article
Language:English
Subjects:
Acute Disease
Acute exacerbations of chronic bronchitis
Anti-Bacterial Agents - therapeutic use
Antibacterial agents
Antibiotics. Antiinfectious agents. Antiparasitic agents
Bacterial Infections - complications
Bacterial Infections - drug therapy
Bacterial Infections - microbiology
Biological and medical sciences
Bronchitis, Chronic - complications
Bronchitis, Chronic - drug therapy
Bronchitis, Chronic - microbiology
Chronic obstructive pulmonary disease
Classification
Haemophilus
Humans
Medical sciences
Moraxella catarrhalis
Pharmacology. Drug treatments
Streptococcus pneumoniae
Treatment
United States
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Summary:In the USA, more than 16 million adults are affected by chronic obstructive pulmonary disease, and chronic bronchitis has been estimated to affect up to 13 million individuals or approximately 4–6% of adults. Chronic bronchitis is an increasing cause of significant morbidity and mortality. During acute exacerbations of chronic bronchitis, subjects experience a worsening of bronchitic symptoms, with an increase from baseline in one or more or the following; dyspnoea, cough and/or sputum volume, purulence or viscosity. The severity of an exacerbation can be graded by how many of these symptoms are present. Antibiotic therapy should be initiated based on patient history and severity of the exacerbation.
ISSN:0924-8579
1872-7913
DOI:10.1016/S0924-8579(01)00404-6