The spectrum of cytotoxic lymphomas of the skin

Cytotoxic lymphomas are peripheral T- and natural killer-cell lymphomas with primary or secondary skin manifestations. They constitute a heterogeneous group of lymphoproliferative disease. They are characterized by expression of cytotoxic proteins and are frequently associated with an aggressive cli...

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Bibliographic Details
Published in:Hautarzt 2000-06, Vol.51 (6), p.390-395
Main Authors: el Shabrawi-Caelen, L, Cerroni, L, Sterry, W, Audring, H, Kerl, H
Format: Article
Language:ger
Subjects:
Humans
Immunophenotyping
Killer Cells, Natural - immunology
Lymphoma, T-Cell, Cutaneous - diagnosis
Lymphoma, T-Cell, Cutaneous - immunology
Lymphoma, T-Cell, Peripheral - diagnosis
Lymphoma, T-Cell, Peripheral - immunology
Skin Neoplasms - diagnosis
Skin Neoplasms - immunology
T-Lymphocytes, Cytotoxic - immunology
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Summary:Cytotoxic lymphomas are peripheral T- and natural killer-cell lymphomas with primary or secondary skin manifestations. They constitute a heterogeneous group of lymphoproliferative disease. They are characterized by expression of cytotoxic proteins and are frequently associated with an aggressive clinical course. A brief introduction to cytotoxic lymphocytes and proteins is followed by a detailed description of clinical, histological, immunohistochemical and genetic characteristics of cutaneous cytotoxic lymphomas.
ISSN:0017-8470