Loading…
Depression in Patients Recovering From a Myocardial Infarction
Depression is common among patients recovering from a myocardial infarction (MI). Approximately 1 in 6 patients with MI experience major depression and at least twice as many as that have significant symptoms of depression soon after the event. Post-MI depression is an independent risk factor for in...
Saved in:
| Published in: | JAMA : the journal of the American Medical Association 2001-10, Vol.286 (13), p.1621-1627 |
|---|---|
| Main Author: | |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-a395t-b2b3163827400d6e14f19f2c33301cbc901ef1de245a6337e8be7881034b86723 |
|---|---|
| cites | |
| container_end_page | 1627 |
| container_issue | 13 |
| container_start_page | 1621 |
| container_title | JAMA : the journal of the American Medical Association |
| container_volume | 286 |
| creator | Ziegelstein, Roy C |
| description | Depression is common among patients recovering from a myocardial infarction
(MI). Approximately 1 in 6 patients with MI experience major depression and
at least twice as many as that have significant symptoms of depression soon
after the event. Post-MI depression is an independent risk factor for increased
mortality. Although the mechanism responsible for this association has not
yet been defined, depression is clearly associated with poor compliance with
risk-reducing recommendations, with abnormalities in autonomic tone that may
make patients more susceptible to ventricular arrhythmias, and with increased
platelet activation. Coronary revascularization procedures also appear to
be used less often in those with post-MI depression than in comparable patients
without mood disorder. Ongoing research will address whether treating depression
improves prognosis. Until this question is answered, efforts should focus
on enhancing adherence to treatment regimens in this group of patients, who
are clearly at risk for noncompliance. Cardiac rehabilitation programs and
increasing levels of social support may help improve symptoms and should be
recommended to all patients. Treatment of depression itself should be individualized
until safety and efficacy are determined for antidepressant therapy in patients
who recently have had an MI. |
| doi_str_mv | 10.1001/jama.286.13.1621 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_71249085</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><ama_id>194244</ama_id><sourcerecordid>71249085</sourcerecordid><originalsourceid>FETCH-LOGICAL-a395t-b2b3163827400d6e14f19f2c33301cbc901ef1de245a6337e8be7881034b86723</originalsourceid><addsrcrecordid>eNpd0VFLwzAQAOAgipvTd32RIuhbay5J0-RFkOl0MFFEn0uapZLRpjNphf17A5sMvJd7uO-O4w6hc8AZYAy3K9WqjAieAc2AEzhAY8ipSGkuxSEaYyxFWjDBRugkhBWOAbQ4RiOAXORM8DG6ezBrb0KwnUusS95Ub43rQ_JudPdjvHVfycx3baKSl02nlV9a1SRzVyuv-9hzio5q1QRztssT9Dl7_Jg-p4vXp_n0fpEqKvM-rUhFgVNBCobxkhtgNciaaEopBl1picHUsDSE5YpTWhhRmUIIwJRVgheETtDNdu7ad9-DCX3Z2qBN0yhnuiGUBRAmscgjvPoHV93gXdytJAAMM0pwRJc7NFStWZZrb1vlN-XfWSK43gEVtGpqr5y2Ye8YlphwGd3F1sU_7KuSEcboL3nMd00</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>211404320</pqid></control><display><type>article</type><title>Depression in Patients Recovering From a Myocardial Infarction</title><source>JAMA Network</source><creator>Ziegelstein, Roy C</creator><creatorcontrib>Ziegelstein, Roy C</creatorcontrib><description>Depression is common among patients recovering from a myocardial infarction
(MI). Approximately 1 in 6 patients with MI experience major depression and
at least twice as many as that have significant symptoms of depression soon
after the event. Post-MI depression is an independent risk factor for increased
mortality. Although the mechanism responsible for this association has not
yet been defined, depression is clearly associated with poor compliance with
risk-reducing recommendations, with abnormalities in autonomic tone that may
make patients more susceptible to ventricular arrhythmias, and with increased
platelet activation. Coronary revascularization procedures also appear to
be used less often in those with post-MI depression than in comparable patients
without mood disorder. Ongoing research will address whether treating depression
improves prognosis. Until this question is answered, efforts should focus
on enhancing adherence to treatment regimens in this group of patients, who
are clearly at risk for noncompliance. Cardiac rehabilitation programs and
increasing levels of social support may help improve symptoms and should be
recommended to all patients. Treatment of depression itself should be individualized
until safety and efficacy are determined for antidepressant therapy in patients
who recently have had an MI.</description><identifier>ISSN: 0098-7484</identifier><identifier>EISSN: 1538-3598</identifier><identifier>DOI: 10.1001/jama.286.13.1621</identifier><identifier>PMID: 11585486</identifier><identifier>CODEN: JAMAAP</identifier><language>eng</language><publisher>Chicago, IL: American Medical Association</publisher><subject>Adult and adolescent clinical studies ; Antidepressive Agents - therapeutic use ; Biological and medical sciences ; Cardiology. Vascular system ; Case studies ; Coronary heart disease ; Depression ; Depression - etiology ; Depression - prevention & control ; Depressive Disorder - etiology ; Depressive Disorder - prevention & control ; Heart ; Heart attacks ; Humans ; Male ; Medical sciences ; Mental depression ; Middle Aged ; Mood disorders ; Mortality ; Myocardial Infarction - physiopathology ; Myocardial Infarction - psychology ; Myocardial Infarction - rehabilitation ; Prognosis ; Psychology. Psychoanalysis. Psychiatry ; Psychopathology. Psychiatry ; Rehabilitation</subject><ispartof>JAMA : the journal of the American Medical Association, 2001-10, Vol.286 (13), p.1621-1627</ispartof><rights>2002 INIST-CNRS</rights><rights>Copyright American Medical Association Oct 3, 2001</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a395t-b2b3163827400d6e14f19f2c33301cbc901ef1de245a6337e8be7881034b86723</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>309,310,314,776,780,785,786,23909,23910,25118,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=14090269$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11585486$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ziegelstein, Roy C</creatorcontrib><title>Depression in Patients Recovering From a Myocardial Infarction</title><title>JAMA : the journal of the American Medical Association</title><addtitle>JAMA</addtitle><description>Depression is common among patients recovering from a myocardial infarction
(MI). Approximately 1 in 6 patients with MI experience major depression and
at least twice as many as that have significant symptoms of depression soon
after the event. Post-MI depression is an independent risk factor for increased
mortality. Although the mechanism responsible for this association has not
yet been defined, depression is clearly associated with poor compliance with
risk-reducing recommendations, with abnormalities in autonomic tone that may
make patients more susceptible to ventricular arrhythmias, and with increased
platelet activation. Coronary revascularization procedures also appear to
be used less often in those with post-MI depression than in comparable patients
without mood disorder. Ongoing research will address whether treating depression
improves prognosis. Until this question is answered, efforts should focus
on enhancing adherence to treatment regimens in this group of patients, who
are clearly at risk for noncompliance. Cardiac rehabilitation programs and
increasing levels of social support may help improve symptoms and should be
recommended to all patients. Treatment of depression itself should be individualized
until safety and efficacy are determined for antidepressant therapy in patients
who recently have had an MI.</description><subject>Adult and adolescent clinical studies</subject><subject>Antidepressive Agents - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Cardiology. Vascular system</subject><subject>Case studies</subject><subject>Coronary heart disease</subject><subject>Depression</subject><subject>Depression - etiology</subject><subject>Depression - prevention & control</subject><subject>Depressive Disorder - etiology</subject><subject>Depressive Disorder - prevention & control</subject><subject>Heart</subject><subject>Heart attacks</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Mental depression</subject><subject>Middle Aged</subject><subject>Mood disorders</subject><subject>Mortality</subject><subject>Myocardial Infarction - physiopathology</subject><subject>Myocardial Infarction - psychology</subject><subject>Myocardial Infarction - rehabilitation</subject><subject>Prognosis</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. Psychiatry</subject><subject>Rehabilitation</subject><issn>0098-7484</issn><issn>1538-3598</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><recordid>eNpd0VFLwzAQAOAgipvTd32RIuhbay5J0-RFkOl0MFFEn0uapZLRpjNphf17A5sMvJd7uO-O4w6hc8AZYAy3K9WqjAieAc2AEzhAY8ipSGkuxSEaYyxFWjDBRugkhBWOAbQ4RiOAXORM8DG6ezBrb0KwnUusS95Ub43rQ_JudPdjvHVfycx3baKSl02nlV9a1SRzVyuv-9hzio5q1QRztssT9Dl7_Jg-p4vXp_n0fpEqKvM-rUhFgVNBCobxkhtgNciaaEopBl1picHUsDSE5YpTWhhRmUIIwJRVgheETtDNdu7ad9-DCX3Z2qBN0yhnuiGUBRAmscgjvPoHV93gXdytJAAMM0pwRJc7NFStWZZrb1vlN-XfWSK43gEVtGpqr5y2Ye8YlphwGd3F1sU_7KuSEcboL3nMd00</recordid><startdate>20011003</startdate><enddate>20011003</enddate><creator>Ziegelstein, Roy C</creator><general>American Medical Association</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7QL</scope><scope>7QP</scope><scope>7TK</scope><scope>7TS</scope><scope>7U7</scope><scope>7U9</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>K9.</scope><scope>M7N</scope><scope>NAPCQ</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>20011003</creationdate><title>Depression in Patients Recovering From a Myocardial Infarction</title><author>Ziegelstein, Roy C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a395t-b2b3163827400d6e14f19f2c33301cbc901ef1de245a6337e8be7881034b86723</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Adult and adolescent clinical studies</topic><topic>Antidepressive Agents - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Cardiology. Vascular system</topic><topic>Case studies</topic><topic>Coronary heart disease</topic><topic>Depression</topic><topic>Depression - etiology</topic><topic>Depression - prevention & control</topic><topic>Depressive Disorder - etiology</topic><topic>Depressive Disorder - prevention & control</topic><topic>Heart</topic><topic>Heart attacks</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Mental depression</topic><topic>Middle Aged</topic><topic>Mood disorders</topic><topic>Mortality</topic><topic>Myocardial Infarction - physiopathology</topic><topic>Myocardial Infarction - psychology</topic><topic>Myocardial Infarction - rehabilitation</topic><topic>Prognosis</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychopathology. Psychiatry</topic><topic>Rehabilitation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ziegelstein, Roy C</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Physical Education Index</collection><collection>Toxicology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>JAMA : the journal of the American Medical Association</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ziegelstein, Roy C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Depression in Patients Recovering From a Myocardial Infarction</atitle><jtitle>JAMA : the journal of the American Medical Association</jtitle><addtitle>JAMA</addtitle><date>2001-10-03</date><risdate>2001</risdate><volume>286</volume><issue>13</issue><spage>1621</spage><epage>1627</epage><pages>1621-1627</pages><issn>0098-7484</issn><eissn>1538-3598</eissn><coden>JAMAAP</coden><abstract>Depression is common among patients recovering from a myocardial infarction
(MI). Approximately 1 in 6 patients with MI experience major depression and
at least twice as many as that have significant symptoms of depression soon
after the event. Post-MI depression is an independent risk factor for increased
mortality. Although the mechanism responsible for this association has not
yet been defined, depression is clearly associated with poor compliance with
risk-reducing recommendations, with abnormalities in autonomic tone that may
make patients more susceptible to ventricular arrhythmias, and with increased
platelet activation. Coronary revascularization procedures also appear to
be used less often in those with post-MI depression than in comparable patients
without mood disorder. Ongoing research will address whether treating depression
improves prognosis. Until this question is answered, efforts should focus
on enhancing adherence to treatment regimens in this group of patients, who
are clearly at risk for noncompliance. Cardiac rehabilitation programs and
increasing levels of social support may help improve symptoms and should be
recommended to all patients. Treatment of depression itself should be individualized
until safety and efficacy are determined for antidepressant therapy in patients
who recently have had an MI.</abstract><cop>Chicago, IL</cop><pub>American Medical Association</pub><pmid>11585486</pmid><doi>10.1001/jama.286.13.1621</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0098-7484 |
| ispartof | JAMA : the journal of the American Medical Association, 2001-10, Vol.286 (13), p.1621-1627 |
| issn | 0098-7484 1538-3598 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_71249085 |
| source | JAMA Network |
| subjects | Adult and adolescent clinical studies Antidepressive Agents - therapeutic use Biological and medical sciences Cardiology. Vascular system Case studies Coronary heart disease Depression Depression - etiology Depression - prevention & control Depressive Disorder - etiology Depressive Disorder - prevention & control Heart Heart attacks Humans Male Medical sciences Mental depression Middle Aged Mood disorders Mortality Myocardial Infarction - physiopathology Myocardial Infarction - psychology Myocardial Infarction - rehabilitation Prognosis Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Rehabilitation |
| title | Depression in Patients Recovering From a Myocardial Infarction |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-30T10%3A49%3A49IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Depression%20in%20Patients%20Recovering%20From%20a%20Myocardial%20Infarction&rft.jtitle=JAMA%20:%20the%20journal%20of%20the%20American%20Medical%20Association&rft.au=Ziegelstein,%20Roy%20C&rft.date=2001-10-03&rft.volume=286&rft.issue=13&rft.spage=1621&rft.epage=1627&rft.pages=1621-1627&rft.issn=0098-7484&rft.eissn=1538-3598&rft.coden=JAMAAP&rft_id=info:doi/10.1001/jama.286.13.1621&rft_dat=%3Cproquest_pubme%3E71249085%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-a395t-b2b3163827400d6e14f19f2c33301cbc901ef1de245a6337e8be7881034b86723%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=211404320&rft_id=info:pmid/11585486&rfr_iscdi=true |