Clinical Factors Associated with Focal Infiltrates in Wheezing Infants and Toddlers

It can be challenging to determine which findings are associated with focal infiltrates in young wheezing children. A prospective study of wheezing children ≤18 months of age revealed focal infiltrates on chest radiograph in 23%. By use of multivariate analysis, findings significantly associated wit...

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Bibliographic Details
Published in:Clinical pediatrics 2000-07, Vol.39 (7), p.387-393
Main Authors: Mahabee-Gittens, E. M., Dowd, M. D., Beck, J. A., Smith, S. Z.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Children & youth
Clinical trials
Female
Health
Humans
Infant
Investigative techniques, diagnostic techniques (general aspects)
Lung - diagnostic imaging
Lung - pathology
Male
Medical sciences
Multivariate Analysis
Oxygen - metabolism
Pediatrics
Pneumonia - complications
Pneumonia - diagnostic imaging
Pneumonia - pathology
Prospective Studies
Radiodiagnosis. Nmr imagery. Nmr spectrometry
Radiography
Respiratory Sounds - etiology
Respiratory system
Risk Factors
Sensitivity and Specificity
X-Rays
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Summary:It can be challenging to determine which findings are associated with focal infiltrates in young wheezing children. A prospective study of wheezing children ≤18 months of age revealed focal infiltrates on chest radiograph in 23%. By use of multivariate analysis, findings significantly associated with focal infiltrates included grunting (OR 4.1, 95% CI, 2.0, 8.6) and oxygen saturation≤93% (OR 2.2, 95% CI, 1.1, 4.8); with a sensitivity and specificity of 12.5% and 97%, respectively. Variables not associated with focal infiltrates included first-time wheezing, fever, and tachypnea. The combination of grunting and oxygen saturation≤93% is highly specific and can be used to help diagnose pneumonia in wheezing infants and toddlers.
ISSN:0009-9228
1938-2707
DOI:10.1177/000992280003900702