Modified capillary electrophoresis system for peptide, protein and double-stranded DNA analysis

The results of high-performance capillary electrophoresis (HPCE) studies of peptide, protein and double-stranded DNA separations on a laboratory-made HPCE system are presented. Parameters of the HPCE system are given. The new method of capillary surface modification by grafting poly(glycidyl methacr...

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Bibliographic Details
Published in:Journal of Chromatography A 2000-05, Vol.879 (2), p.189-196
Main Authors: Belenkii, Boris G, Kassalainen, Galina E, Nasledov, Dmitry G
Format: Article
Language:English
Subjects:
DNA
DNA - analysis
Electrophoresis, Capillary - methods
Peptides
Peptides - analysis
Poly(glycidyl methacrylate)
Proteins
Proteins - analysis
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Summary:The results of high-performance capillary electrophoresis (HPCE) studies of peptide, protein and double-stranded DNA separations on a laboratory-made HPCE system are presented. Parameters of the HPCE system are given. The new method of capillary surface modification by grafting poly(glycidyl methacrylate) is described. The problems of HPCE biopolymer analysis connected with the sample–wall interactions are discussed.
ISSN:0021-9673
DOI:10.1016/S0021-9673(00)00226-0