Antimicrobial constituents of the leaves of Acalypha wilkesiana and Aacalypha hispida

An activity directed fractionation of a 50% aqueous ethanol extract of A. wilkesiana and A. hispida leaves resulted in the isolation of gallic acid, corilagin and geraniin as the compounds responsible for the observed antimicrobial activity. Quercetin 3-O-rutinoside and kaempferol 3-O-rutinoside wer...

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Bibliographic Details
Published in:Phytotherapy research 2000-08, Vol.14 (5), p.371-374
Main Authors: Adesina, S K, Idowu, O, Ogundaini, A O, Oladimeji, H, Olugbade, T A, Onawunmi, G O, Pais, M
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - chemistry
Anti-Bacterial Agents - pharmacology
Euphorbiaceae - chemistry
Glucosides - chemistry
Humans
Hydrolyzable Tannins
Magnetic Resonance Spectroscopy
Microbial Sensitivity Tests
Plant Extracts - chemistry
Plant Extracts - pharmacology
Plant Leaves - chemistry
Plants, Medicinal - chemistry
Tannins
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Summary:An activity directed fractionation of a 50% aqueous ethanol extract of A. wilkesiana and A. hispida leaves resulted in the isolation of gallic acid, corilagin and geraniin as the compounds responsible for the observed antimicrobial activity. Quercetin 3-O-rutinoside and kaempferol 3-O-rutinoside were also isolated from the inactive fraction of A. hispida. The structures were established by permethylation, 2D - NMR ((1)H and (13)C) and MS data.
ISSN:0951-418X