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Characterization of the chitin biosynthesis process as a compensatory mechanism in the fks1 mutant of Saccharomyces cerevisiae
Deletion of the 1,3-β- D-glucan synthase gene FKS1 in Saccharomyces cerevisiae induces a compensatory mechanism that is reflected in a significant increase in chitin synthase III (CSIII) activity, leading to high rates of chitin synthesis. Deregulation of CSIII activity is mainly due to the intracel...
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| Published in: | FEBS letters 2000-07, Vol.478 (1), p.84-88 |
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| Main Authors: | , , , , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c5394-6382089679b05fd20699a7aafd37d659242c78836e8792504949a2ed293e47583 |
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| cites | cdi_FETCH-LOGICAL-c5394-6382089679b05fd20699a7aafd37d659242c78836e8792504949a2ed293e47583 |
| container_end_page | 88 |
| container_issue | 1 |
| container_start_page | 84 |
| container_title | FEBS letters |
| container_volume | 478 |
| creator | Garcı́a-Rodriguez, L.J Trilla, J.A Castro, C Valdivieso, M.H Durán, A Roncero, C |
| description | Deletion of the 1,3-β-
D-glucan synthase gene
FKS1 in
Saccharomyces cerevisiae induces a compensatory mechanism that is reflected in a significant increase in chitin synthase III (CSIII) activity, leading to high rates of chitin synthesis. Deregulation of CSIII activity is mainly due to the intracellular delocalization of Chs3p and Chs4p, the two main components of the CSIII active complex. |
| doi_str_mv | 10.1016/S0014-5793(00)01835-4 |
| format | article |
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D-glucan synthase gene
FKS1 in
Saccharomyces cerevisiae induces a compensatory mechanism that is reflected in a significant increase in chitin synthase III (CSIII) activity, leading to high rates of chitin synthesis. Deregulation of CSIII activity is mainly due to the intracellular delocalization of Chs3p and Chs4p, the two main components of the CSIII active complex.</description><identifier>ISSN: 0014-5793</identifier><identifier>EISSN: 1873-3468</identifier><identifier>DOI: 10.1016/S0014-5793(00)01835-4</identifier><identifier>PMID: 10922474</identifier><language>eng</language><publisher>England: Elsevier B.V</publisher><subject>Carrier Proteins - metabolism ; Cell Division ; Chitin ; Chitin - biosynthesis ; Chitin Synthase - biosynthesis ; Chitin Synthase - metabolism ; Chitin synthase III activity ; Compensatory mechanism ; Echinocandins ; Enzyme Induction ; Fungal Proteins - biosynthesis ; Fungal Proteins - genetics ; Fungal Proteins - metabolism ; Fungal Proteins - physiology ; Gene Deletion ; Gene Expression Regulation, Fungal ; Glucosyltransferases ; Membrane Proteins - deficiency ; Membrane Proteins - genetics ; Membrane Proteins - physiology ; Phenotype ; Saccharomyces cerevisiae - cytology ; Saccharomyces cerevisiae - enzymology ; Saccharomyces cerevisiae - genetics ; Saccharomyces cerevisiae - metabolism ; Saccharomyces cerevisiae Proteins</subject><ispartof>FEBS letters, 2000-07, Vol.478 (1), p.84-88</ispartof><rights>2000 Federation of European Biochemical Societies</rights><rights>FEBS Letters 478 (2000) 1873-3468 © 2015 Federation of European Biochemical Societies</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5394-6382089679b05fd20699a7aafd37d659242c78836e8792504949a2ed293e47583</citedby><cites>FETCH-LOGICAL-c5394-6382089679b05fd20699a7aafd37d659242c78836e8792504949a2ed293e47583</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0014579300018354$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,780,784,3549,27924,27925,45780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10922474$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Garcı́a-Rodriguez, L.J</creatorcontrib><creatorcontrib>Trilla, J.A</creatorcontrib><creatorcontrib>Castro, C</creatorcontrib><creatorcontrib>Valdivieso, M.H</creatorcontrib><creatorcontrib>Durán, A</creatorcontrib><creatorcontrib>Roncero, C</creatorcontrib><title>Characterization of the chitin biosynthesis process as a compensatory mechanism in the fks1 mutant of Saccharomyces cerevisiae</title><title>FEBS letters</title><addtitle>FEBS Lett</addtitle><description>Deletion of the 1,3-β-
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FKS1 in
Saccharomyces cerevisiae induces a compensatory mechanism that is reflected in a significant increase in chitin synthase III (CSIII) activity, leading to high rates of chitin synthesis. 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FKS1 in
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| identifier | ISSN: 0014-5793 |
| ispartof | FEBS letters, 2000-07, Vol.478 (1), p.84-88 |
| issn | 0014-5793 1873-3468 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_71265658 |
| source | ScienceDirect Journals; Wiley-Blackwell Read & Publish Collection |
| subjects | Carrier Proteins - metabolism Cell Division Chitin Chitin - biosynthesis Chitin Synthase - biosynthesis Chitin Synthase - metabolism Chitin synthase III activity Compensatory mechanism Echinocandins Enzyme Induction Fungal Proteins - biosynthesis Fungal Proteins - genetics Fungal Proteins - metabolism Fungal Proteins - physiology Gene Deletion Gene Expression Regulation, Fungal Glucosyltransferases Membrane Proteins - deficiency Membrane Proteins - genetics Membrane Proteins - physiology Phenotype Saccharomyces cerevisiae - cytology Saccharomyces cerevisiae - enzymology Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins |
| title | Characterization of the chitin biosynthesis process as a compensatory mechanism in the fks1 mutant of Saccharomyces cerevisiae |
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