New Isomalabaricane Derivatives from a New Species of Jaspis Sponge Collected at the Vanuatu Islands

Six new cytotoxic isomalabaricane-type triterpenoids and nortriterpenoids with a 3α-acetoxy group were isolated, along with the known globostellatic acids B (1) and C (2), from the marine sponge Jaspis sp. collected at Vanuatu Island. The structures were determined by 2D NMR data and by comparison w...

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Bibliographic Details
Published in:Journal of natural products (Washington, D.C.) D.C.), 2000-07, Vol.63 (7), p.943-946
Main Authors: Zampella, Angela, D'Auria, Maria Valeria, Debitus, Cécile, Menou, Jean-Louis
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
General pharmacology
isomalabaricane derivatives
Jaspis
Medical sciences
Molecular Structure
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Porifera - chemistry
Spectrum Analysis
triterpenoids
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Summary:Six new cytotoxic isomalabaricane-type triterpenoids and nortriterpenoids with a 3α-acetoxy group were isolated, along with the known globostellatic acids B (1) and C (2), from the marine sponge Jaspis sp. collected at Vanuatu Island. The structures were determined by 2D NMR data and by comparison with spectral data of known related compounds.
ISSN:0163-3864
1520-6025
DOI:10.1021/np000088u