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Plasma levels of C-reactive protein after coronary stent implantation

Aims This study was designed to investigate the role of inflammation on the occurrence of angiographic restenosis 6 months after coronary stent implantation and the influence of different kinds of antithrombotic and antiplatelet strategies on inflammation. Methods and Results In an open randomized t...

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Bibliographic Details
Published in:European heart journal 2000-07, Vol.21 (14), p.1152-1158
Main Authors: Gottsauner-Wolf, M., Zasmeta, G., Hornykewycz, S., Nikfardjam, M., Stepan, E., Wexberg, P., Zorn, G., Glogar, D., Probst, P., Maurer, G., Huber, K.
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Language:English
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Summary:Aims This study was designed to investigate the role of inflammation on the occurrence of angiographic restenosis 6 months after coronary stent implantation and the influence of different kinds of antithrombotic and antiplatelet strategies on inflammation. Methods and Results In an open randomized trial, 40 consecutive patients were treated with aspirin (100mg.day−1) and either ticlopidine (2×250mg.day−1) (n=17), or phenprocoumon (INR 2·0–3·0) and dipyridamole (3×160mg.day−1) (n=23) after successful elective coronary stent implantation. Plasma levels of C-reactive protein were determined one day before stent implantation and serially thereafter twice daily up to 120h. C-reactive protein plasma levels increased significantly (P
ISSN:0195-668X
1522-9645
DOI:10.1053/euhj.1999.1987