Separation of phenols as neutral compounds by micellar electrokinetic capillary chromatography

Separation of phenols as neutral solutes by micellar electrokinetic capillary chromatography provides a quantitative linear dynamic range of 6000–13 000. Since the compounds are injected and separated as neutral solutes, the dispersive processes of anti-stacking and electrodispersion are eliminated....

Full description

Saved in:
Bibliographic Details
Published in:Journal of Chromatography A 2003-10, Vol.1014 (1), p.179-187
Main Authors: Sayler, Kari, Weinberger, Robert
Format: Article
Language:English
Subjects:
Analytical chemistry
Chemistry
Chromatographic methods and physical methods associated with chromatography
Chromatography, High Pressure Liquid
Chromatography, Micellar Electrokinetic Capillary - methods
Exact sciences and technology
Hydrogen-Ion Concentration
Other chromatographic methods
Phenols
Phenols - chemistry
Phenols - isolation & purification
Sensitivity and Specificity
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Separation of phenols as neutral solutes by micellar electrokinetic capillary chromatography provides a quantitative linear dynamic range of 6000–13 000. Since the compounds are injected and separated as neutral solutes, the dispersive processes of anti-stacking and electrodispersion are eliminated. Optimized conditions allow for sub-ppm quantitation of trace impurities in the presence of the major components at various stages of the production of high purity phenols. The background electrolyte consists of 100 m M sodium dodecyl sulfate in 50 m M phosphate buffer pH 7. The method is precise, reliable, and the limits of detection are superior compared to HPLC by a factor of 20.
ISSN:0021-9673
DOI:10.1016/S0021-9673(03)00576-4