Preparing for Elimination of Congenital Rubella Syndrome (CRS): Summary of a Workshop on CRS Elimination in the United States

The goal of eliminating indigenous rubella and congenital rubella syndrome (CRS) in the United States in the near future is now within reach, because rubella incidence has been sustained at record-low levels since the mid-1990s. Effective prevention strategies to eliminate CRS and rubella require im...

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Bibliographic Details
Published in:Clinical infectious diseases 2000-07, Vol.31 (1), p.85-95
Main Authors: Reef, Susan E., Plotkin, Stanley, Cordero, José F., Katz, Michael, Cooper, Louis, Schwartz, Benjamin, Zimmerman-Swain, Laura, Danovaro-Holliday, Maria Carolina, Wharton, Melinda
Format: Article
Language:English
Subjects:
Auditory defects
Biological and medical sciences
Clinical Articles
Congenital rubella syndrome
Epidemiology
Hearing loss
Human viral diseases
Humans
Infants
Infections
Infectious diseases
Medical sciences
Neonatal screening
Pediatrics
Rubella
Rubella Syndrome, Congenital - diagnosis
Rubella Syndrome, Congenital - epidemiology
Rubella Syndrome, Congenital - prevention & control
Surveillance
United States - epidemiology
Viral diseases
Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye
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Summary:The goal of eliminating indigenous rubella and congenital rubella syndrome (CRS) in the United States in the near future is now within reach, because rubella incidence has been sustained at record-low levels since the mid-1990s. Effective prevention strategies to eliminate CRS and rubella require improvement in the surveillance of CRS and congenital rubella infection (CRI). The purpose of the workshop was to review rubella and CRS epidemiology, as well as current clinical, diagnostic, and laboratory practices, to determine whether new strategies are needed to achieve and document CRS elimination. Workshop participants agreed that surveillance for CRS must be strengthened, particularly through augmented laboratory capabilities, and the case definition for CRS must be revised to reflect the current scientific information available. Further studies of methods are needed to identify high-risk populations and geographic areas for rubella and CRS and to enhance identification of infants with CRS.
ISSN:1058-4838
1537-6591
DOI:10.1086/313928