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Bi- and Tricyclic Nucleoside Derivatives Restricted in S-Type Conformations and Obtained by RCM-Reactions

Ring-closing metathesis (RCM) is applied as a new and powerful technology in the construction of nucleoside analogues that are conformationally restricted in S-type conformations due to additional 3′,4′- and/or 3′,5′-linkages.

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Bibliographic Details
Published in:Nucleosides, nucleotides & nucleic acids nucleotides & nucleic acids, 2003-10, Vol.22 (5-8), p.723-725
Main Authors: Albæk, Nanna, Ravn, Jacob, Freitag, Morten, Thomasen, Helena, Christensen, Nanna K., Petersen, Michael, Nielsen, Poul
Format: Article
Language:English
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Summary:Ring-closing metathesis (RCM) is applied as a new and powerful technology in the construction of nucleoside analogues that are conformationally restricted in S-type conformations due to additional 3′,4′- and/or 3′,5′-linkages.
ISSN:1525-7770
1532-2335
DOI:10.1081/NCN-120022619