Effects of yogurt supplemented with brewer's yeast cell wall on constipation and intestinal microflora in rats

Brewer's yeast cell wall (BYC) is a valuable foodstuff that prevents constipation in rats. In this study, the effects of yogurt supplemented with brewer's yeast cell wall (BYC-Y) on constipated male Sprague-Dawley rats induced by loperamide (2 mg/kg body weight) were investigated. The prev...

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Bibliographic Details
Published in:Journal of Nutritional Science and Vitaminology 2001, Vol.47(6), pp.367-372
Main Authors: Nakamura, T. (Kirin Brewery Co. Ltd., Takasaki, Gunma (Japan). Research Labs.), Nishida, S, Mizutani, M, Iino, H
Format: Article
Language:English
Subjects:
Animals
Antidiarrheals - therapeutic use
Biological and medical sciences
bowel movement
BREWERS' YEAST
Cell Wall - chemistry
CELL WALLS
constipation
Constipation - chemically induced
Constipation - diet therapy
Constipation - microbiology
Defecation - drug effects
Dietary Supplements
DIGESTIVE DISORDERS
General pharmacology
intestinal microflora
INTESTINES
Intestines - microbiology
Loperamide - therapeutic use
Male
Medical sciences
MICROBIAL FLORA
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
RATS
Rats, Sprague-Dawley
SUPPLEMENTS
yeast cell wall
Yeast, Dried - therapeutic use
YOGHURT
Yogurt
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Summary:Brewer's yeast cell wall (BYC) is a valuable foodstuff that prevents constipation in rats. In this study, the effects of yogurt supplemented with brewer's yeast cell wall (BYC-Y) on constipated male Sprague-Dawley rats induced by loperamide (2 mg/kg body weight) were investigated. The preventive effect of BYC-Y on experimentally constipated rats was examined and compared with that of nonfiber diet (Control) and standard yogurt (Yogurt) as the control diets. The number of feces and fecal dry weight were greater in rats fed with BYC-Y than in those fed with Control or Yogurt. Moreover, the effect of BYC on the improvement of cecal microflora in constipated experimental model rats was evaluated. The number of Lactobacillus, Eubacterium, and total anaerobes per unit cecal contents increased (p < 0.03) as a result of BYC ingestion. These findings indicate that BYC-Y or BYC is effective for the alleviation of constipation and bowel environment.
ISSN:0301-4800
1881-7742
DOI:10.3177/jnsv.47.367