Pathology and immunohistochemistry in three species of salmonids after experimental infection with Flavobacterium psychrophilum

Rainbow trout, Oncorhynchus mykiss (Walbaum), sea trout, Salmo trutta L., and Atlantic salmon, Salmo salar L., were experimentally infected with Flavobacterium psychrophilum in order to evaluate any species differences in susceptibility to the bacterium. Furthermore, differences in pathological chan...

Full description

Saved in:
Bibliographic Details
Published in:Journal of fish diseases 2003-09, Vol.26 (9), p.529-538
Main Authors: Ekman, E, Norrgren, L
Format: Article
Language:English
Subjects:
Animals
Atlantic salmon
Brackish
Disease Susceptibility - veterinary
Fish Diseases - metabolism
Fish Diseases - pathology
Flavobacteriaceae Infections - metabolism
Flavobacteriaceae Infections - pathology
Flavobacteriaceae Infections - veterinary
Flavobacterium - pathogenicity
Flavobacterium psychrophilum
Freshwater
Immunohistochemistry
Marine
Oncorhynchus mykiss
pathology
rainbow trout
Salmo salar
Salmo trutta
Salmon - microbiology
sea trout
susceptibility
Sweden
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Rainbow trout, Oncorhynchus mykiss (Walbaum), sea trout, Salmo trutta L., and Atlantic salmon, Salmo salar L., were experimentally infected with Flavobacterium psychrophilum in order to evaluate any species differences in susceptibility to the bacterium. Furthermore, differences in pathological changes and distribution of the bacteria in internal organs were studied. The bacteria were injected intraperitoneally in two doses, high dose (Hd) 1 × 107 colony forming units (CFU) fish−1 and low dose (Ld) 1 × 106 CFU fish−1. The mortalities in the Ld groups varied between 0 and 7.5% and in the Hd groups between 55–70%. No significant differences in mortality between the species were recorded. Clinical signs and pathological findings were similar in the three species and in accordance with those of rainbow trout fry syndrome. Rainbow trout showed more pronounced lesions in the spleen compared with the other species. Necrosis of renal tubular epithelium and haematopoietic tissue was most prominent in rainbow trout and Atlantic salmon. Intracellular eosinophilic droplets in the kidney tubular epithelium were a prominent finding in rainbow trout and sea trout surviving the infection. The distribution of the bacteria in internal organs was similar in the three species, as studied with immunohistochemistry.
ISSN:0140-7775
1365-2761
DOI:10.1046/j.1365-2761.2003.00487.x