Safety and Efficacy of Influenza Vaccine in Children

OBJECTIVE: To describe the safety and efficacy of influenza vaccines in asthmatic children. DATA SOURCES: Literature was identified by a MEDLINE search (2002–March 2003). Key search terms included asthma, exacerbation, children, vaccine, and influenza. DATA SYNTHESIS: Concerns that the influenza vac...

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Bibliographic Details
Published in:The Annals of pharmacotherapy 2003-11, Vol.37 (11), p.1712-1715
Main Author: Goldstein, Leslie GB
Format: Article
Language:English
Subjects:
Asthma - complications
Biological and medical sciences
Clinical Trials as Topic
Humans
Influenza Vaccines - administration & dosage
Influenza Vaccines - adverse effects
Influenza Vaccines - immunology
Medical sciences
Miscellaneous
Pharmacology. Drug treatments
Risk Factors
Vaccines, Attenuated - adverse effects
Vaccines, Inactivated - adverse effects
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Summary:OBJECTIVE: To describe the safety and efficacy of influenza vaccines in asthmatic children. DATA SOURCES: Literature was identified by a MEDLINE search (2002–March 2003). Key search terms included asthma, exacerbation, children, vaccine, and influenza. DATA SYNTHESIS: Concerns that the influenza vaccine may exacerbate asthma attacks have kept many asthmatic children from receiving this immunization. Researchers have conducted studies to determine the burden of influenza on asthmatic children, the safety of influenza vaccines, and their benefit in the presence of glucocorticoid burst therapy in the same population. CONCLUSIONS: Influenza vaccines tested are safe and efficacious in asthmatic children.
ISSN:1060-0280
1542-6270
DOI:10.1345/aph.1D009