Physiology of aging

Although physiological deterioration occurs with advancing adult age, the interpretation of cross-sectional and longitudinal studies of age-changes in physiological processes are often complicated by confounders unrelated to aging. Age-associated disease is a major cause of physiological deteriorati...

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Bibliographic Details
Published in:International journal of sport nutrition and exercise metabolism 2001-12, Vol.11 Suppl (s1), p.S218-S222
Main Author: Masoro, E J
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Aging - physiology
Female
Health Status
Humans
Longevity
Male
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Summary:Although physiological deterioration occurs with advancing adult age, the interpretation of cross-sectional and longitudinal studies of age-changes in physiological processes are often complicated by confounders unrelated to aging. Age-associated disease is a major cause of physiological deterioration. To avoid this factor, only subjects free of discernible disease are used in many studies of what is referred to as "normal" aging. However, it is important to recognize that age-associated disease is not only a common occurrence but also an integral part of aging. Increasingly, gene-environment interactions are recognized as playing a major role in age-associated physiological deterioration, and there is great individual variation in both the rate of aging and the occurrence of age-associated physiological deterioration.
ISSN:1526-484X
1543-2742
DOI:10.1123/ijsnem.11.s1.s218