Molecular cloning of three nonhuman primate follicle stimulating hormone β-subunit cDNAs

The follicle stimulating hormone (FSH) β‐subunit cDNAs were cloned and sequenced for an old world primate, the rhesus monkey (Macaca mulatta), and two New World primates, the common marmoset (Callithrix jacchus) and pygmy marmoset (Cebuella pygmaea). The cDNA and predicted amino acid sequences of th...

Full description

Saved in:
Bibliographic Details
Published in:Journal of medical primatology 2001-12, Vol.30 (6), p.299-303
Main Authors: Wolfgang, M.J., Grendell, R.L., Golos, T.G.
Format: Article
Language:English
Subjects:
Amino Acid Sequence
Animals
Base Sequence
Callithrix - genetics
Callitrichinae - genetics
Cattle
Cloning, Molecular
DNA, Complementary - genetics
Follicle Stimulating Hormone - chemistry
Follicle Stimulating Hormone - genetics
Follicle Stimulating Hormone, beta Subunit
gonadotropin
Humans
Macaca mulatta - genetics
Mice
Molecular Sequence Data
pituitary
Protein Subunits
sequence
Sheep
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The follicle stimulating hormone (FSH) β‐subunit cDNAs were cloned and sequenced for an old world primate, the rhesus monkey (Macaca mulatta), and two New World primates, the common marmoset (Callithrix jacchus) and pygmy marmoset (Cebuella pygmaea). The cDNA and predicted amino acid sequences of the rhesus monkey FSH β‐subunit were related most closely to the human FSH β‐subunit (>96% identity). The common and pygmy marmosets have identical FSH β‐subunit cDNAs, whereas the marmoset FSH β‐subunit diverges from the rhesus and human molecules with less than 93% identity. These results have significance for the implementation of assisted reproductive technologies in the nonhuman primate as well as the evolution of genes encoding reproductive hormones.
ISSN:0047-2565
1600-0684
DOI:10.1034/j.1600-0684.2001.300602.x