Methylphenidate in a Patient with Depression and Respiratory Insufficiency

Objective: We report a case of severe depression in an elderly and critically ill patient with multiple medical complications who was treated with a combination of methylphenidate and sertraline. The objective of this report is to outline the usefulness of methylphenidate as an antidepressant in a p...

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Bibliographic Details
Published in:International journal of psychiatry in medicine 2001-01, Vol.31 (4), p.443-449
Main Authors: Ayache, Danusa Céspedes Guizzo, Júnior, Renério Fráguas
Format: Article
Language:English
Subjects:
Aged
Antidepressive Agents - therapeutic use
Biological and medical sciences
Central Nervous System Stimulants - therapeutic use
Depressive Disorder - drug therapy
Dose-Response Relationship, Drug
Drug Therapy, Combination
Humans
Male
Medical sciences
Mental depression
Methylphenidate - therapeutic use
Neuropharmacology
Pharmacology. Drug treatments
Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease)
Psychology. Psychoanalysis. Psychiatry
Psychopharmacology
Respiratory Insufficiency - drug therapy
Respiratory Insufficiency - psychology
Sertraline - therapeutic use
Stimulants
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Summary:Objective: We report a case of severe depression in an elderly and critically ill patient with multiple medical complications who was treated with a combination of methylphenidate and sertraline. The objective of this report is to outline the usefulness of methylphenidate as an antidepressant in a patient with respiratory insufficiency. Method: Case description. Results: The patient had a positive clinical response with initial mental confusion due to methylphenidate. An initial dose of 2.5 mg/day allowed antidepressant response and improvement of respiratory function permitting the removal of mechanical ventilation. Conclusion: Methylphenidate may be useful for patients with severe medical conditions including ventilatory insufficiency.
ISSN:0091-2174
1541-3527
DOI:10.2190/CXNE-0UFR-7Q04-CQ3M